FAM161B and ISY1-RAB43

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM161B	ISY1-RAB43
Description		FAM161 centrosomal protein B	ISY1-RAB43 readthrough
Image		No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Cytoplasmic Microtubule Microtubule Cytoskeleton
	Molecular Function	Protein Binding
	Biological Process	Cilium Organization
Pathways			Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Serum uric acid levels ( 29559957)	Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
Interacting Genes		70 interacting genes: ABI2 BICD2 BLOC1S2 BORCS6 CARD9 CBY1 CCDC125 CCDC13 CCDC136 CCDC138 CCDC172 CCDC57 CCDC83 CCDC88B CDR2L CEP55 CEP70 CINP CTNNA3 DDI1 DRC4 EXOSC8 GOLGA2 GOLGA6A GOLGA6L9 GPSM1 HAUS1 HOMER3 HOOK2 HSF2BP ISY1-RAB43 KIAA1328 LZTS1 MAPRE3 MDFI MEIS3 MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NR3C1 OIP5 PICK1 PLAGL2 PNMA1 PPP2R3C RINT1 SH3BP5L SMAD2 SPDEF SRGAP2B STX11 STX1B SYCE1 TEX11 TEX12 TFIP11 TRAF1 TRAF2 TRIM15 TSGA10 TSNAXIP1 TTC23 TTC23L USH1G USHBP1 VPS52 ZC4H2 ZRANB1	14 interacting genes: CCDC185 EXOC8 FAM161B FARS2 FBXO44 FRS3 LENG1 NME7 NXF1 RCOR3 TSTD2 UBASH3A ZNF587 ZNF629
Entrez ID		145483	100534599
HPRD ID		12649
Ensembl ID		ENSG00000156050	ENSG00000261796
Uniprot IDs		Q96MY7	Q9ULR0
PDB IDs			5YZG 6FF7 6ZYM 7A5P 8C6J 8CH6 8I0W 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		Cytoskeleton Centrosome Identical Protein Binding Microtubule Cytoskeleton Organization Organelle Organization Microtubule-based Process Central Element Protein Binding Cytoskeleton Organization Cytoplasm Microtubule Binding Synaptonemal Complex Assembly Synaptonemal Complex Synaptonemal Complex Organization Cytoskeleton-dependent Intracellular Transport Dynein Light Intermediate Chain Binding Microtubule Nucleation Signaling Adaptor Activity Organelle Transport Along Microtubule Regulation Of Lysosome Size BORC Complex Microtubule Cell Division Organelle Localization Thioesterase Binding Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Golgi Cis Cisterna Vesicle Fusion To Plasma Membrane Regulation Of Endosome Size
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