ISY1-RAB43 and CCDC185

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ISY1-RAB43	CCDC185
Description		ISY1-RAB43 readthrough	coiled-coil domain containing 185
Image			No pdb structure
GO Annotations	Cellular Component
	Molecular Function		Protein Binding
	Biological Process
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
Interacting Genes		14 interacting genes: CCDC185 EXOC8 FAM161B FARS2 FBXO44 FRS3 LENG1 NME7 NXF1 RCOR3 TSTD2 UBASH3A ZNF587 ZNF629	49 interacting genes: AMOTL2 BACH2 CADPS CALCOCO2 CBY2 CCDC136 CCDC85B CDR2L CEP44 CEP57 EVI5 EVI5L FAM161A GEMIN4 GOLGA2 GOLGA6L9 GRIPAP1 HSF2BP IKZF1 ISY1-RAB43 KRT15 KRT27 KRT35 KRT40 KRTAP10-7 KRTAP4-12 KXD1 LURAP1 MAGEA11 MAGEA2 MAGEA2B MAGEA6 MCC MDFI MID2 MKRN3 MTUS2 NAP1L2 NUTM1 PDLIM7 PKNOX2 PPP1R12C SPRED1 SPTA1 TBC1D1 TRAF1 TRIM27 VPS52 ZRANB1
Entrez ID		100534599	164127
HPRD ID			08761
Ensembl ID		ENSG00000261796	ENSG00000178395
Uniprot IDs		Q9ULR0	Q8N715
PDB IDs		5YZG 6FF7 6ZYM 7A5P 8C6J 8CH6 8I0W 8RO2 9FMD
Enriched GO Terms of Interacting Partners?			Keratin Filament Cytoskeleton Intermediate Filament Structural Constituent Of Skin Epidermis Negative Regulation Of Protein Acetylation Intermediate Filament Organization Microtubule Binding Protein Binding Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytosol PML Body Negative Regulation Of Protein Sumoylation Histone Deacetylase Binding Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Viral Transcription Identical Protein Binding Suppression Of Viral Release By Host
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