CSNK1D and PPP1R14A

Number of citations of the paper that reports this interaction (PubMedID 15003508)
0

Data Source:
HPRD (in vitro)

		CSNK1D	PPP1R14A
Description		casein kinase 1 delta	protein phosphatase 1 regulatory inhibitor subunit 14A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Cytoskeleton Spindle Microtubule Plasma Membrane Cilium Actin Cytoskeleton Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Ciliary Basal Body Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Cadherin Binding Tau-protein Kinase Activity Protein Serine Kinase Activity	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity
	Biological Process	Protein Phosphorylation Endocytosis Microtubule Nucleation Golgi Organization Signal Transduction Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Protein Localization To Golgi Apparatus Regulation Of Circadian Rhythm COPII Vesicle Coating Rhythmic Process Spindle Assembly Protein Localization To Cilium Protein Localization To Centrosome Positive Regulation Of Canonical Wnt Signaling Pathway Midbrain Dopaminergic Neuron Differentiation Non-motile Cilium Assembly Positive Regulation Of Non-canonical Wnt Signaling Pathway	Cellular Response To Xenobiotic Stimulus
Pathways		COPII-mediated vesicle transport Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2 The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex Phosphorylation and nuclear translocation of the CRY:PER:kinase complex	RHO GTPases activate PKNs
Drugs
Diseases
GWAS			Diverticular disease ( 30177863)
Interacting Genes		43 interacting genes: AKAP9 APP ARFGAP1 ATM BACE1 BRCA1 CCDC14 CDK5 CREB1 CTNNB1 DRICH1 DVL1 DVL3 EVI5 GJA1 HIF1A IKZF4 JPT2 KDR LURAP1 PAK5 PDPK1 PER1 PER2 PER3 PPP1R14A PPP5C PSEN2 PTPRD RAB1A SHANK3 SMAD2 SMAD3 SMURF1 SNAPIN SNCA TP53 TRIM3 TRIM9 YAP1 YWHAZ ZBTB8A ZNF618	16 interacting genes: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DAPK1 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ
Entrez ID		1453	94274
HPRD ID		02920	16291
Ensembl ID		ENSG00000141551	ENSG00000167641
Uniprot IDs		H7BYT1 P48730	Q96A00
PDB IDs		3UYS 3UYT 3UZP 4HGT 4HNF 4KB8 4KBA 4KBC 4KBK 4TN6 4TW9 4TWC 5IH4 5IH5 5IH6 5MQV 5OKT 5W4W 6F1W 6F26 6GZM 6HMP 6HMR 6PXN 6PXO 6PXP 6RCG 6RCH 6RU6 6RU7 6RU8 7NZY 7P7F 7P7G 7P7H 7QR9 7QRA 7QRB 8D7M 8D7N 8D7O 8D7P 8IZC 8VXD 8VXF 9B3S
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Communication Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Cellular Component Organization Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription Cis-regulatory Region Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Multicellular Organismal Process Transcription Corepressor Binding Enzyme Binding Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Signal Release Response To Radiation Regulation Of Neuron Apoptotic Process Organelle Localization Negative Regulation Of Apoptotic Process Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Cellular Response To Oxygen-containing Compound Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Signal Transduction Negative Regulation Of Programmed Cell Death Cytoplasm Ubiquitin Protein Ligase Binding I-SMAD Binding Positive Regulation Of Developmental Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Membrane Potential Regulation Of Organelle Organization Tissue Development Negative Regulation Of Biosynthetic Process Transcription Coactivator Binding Regulation Of Growth Regulation Of Neurogenesis Positive Regulation Of Multicellular Organismal Process Entrainment Of Circadian Clock By Photoperiod Regulation Of Protein Stability Establishment Of Organelle Localization Developmental Growth Epithelial Tube Morphogenesis Negative Regulation Of Signaling Negative Regulation Of Cell Communication Positive Regulation Of Cellular Component Organization Regulation Of Developmental Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase Activity Kinase Activity Protein Phosphorylation Phosphorylation Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling ATP Binding Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Signal Transduction Nucleotide Binding Transferase Activity Regulation Of Signal Transduction Signal Transduction Protein Modification Process Regulation Of Canonical Wnt Signaling Pathway Phosphate-containing Compound Metabolic Process Regulation Of Wnt Signaling Pathway Protein Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Intracellular Signal Transduction Wnt Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Catabolic Process Regulation Of Protein Localization Cytoplasm Regulation Of Proteolysis Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Localization Endocytosis Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Golgi Organization Response To Norepinephrine Cellular Response To Norepinephrine Stimulus Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Cytosol Negative Regulation Of Apoptotic Process Plasma Membrane Negative Regulation Of Programmed Cell Death Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Synaptic Transmission Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Protein Metabolic Process Import Into Cell Regulation Of Cellular Component Organization Response To Stress
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