SPMIP5 and GPSM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPMIP5	GPSM3
Description		sperm microtubule inner protein 5	G protein signaling modulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection	Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding GTPase Regulator Activity
	Biological Process		Positive Regulation Of Leukocyte Chemotaxis Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways			G alpha (i) signalling events
Drugs
Diseases
GWAS			A body shape index ( 34021172) Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: ANKRD11 BCAS2 FNDC3B GPSM3 MKRN3 MYOZ3 SPG21 TEX11	44 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KCNJ5-AS1 KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPMIP5 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 ZNF20 ZNF581
Entrez ID		143379	63940
HPRD ID		12592	13605
Ensembl ID		ENSG00000165863	ENSG00000213654
Uniprot IDs		Q8WW14	A0A024RCP6 Q9Y4H4
PDB IDs
Enriched GO Terms of Interacting Partners?			Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex
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