CRYBB3 and DOK6

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		CRYBB3	DOK6
Name		crystallin beta B3	docking protein 6
Structure			No pdb structure
GO Annotations	Cellular Component	None	Cytoplasm Cytosol
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding	Protein Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Pathways		None	RET signaling
GWAS		No GWAS studies recorded	Bone fracture in osteoporosis ( 28580392 ) Caudate activity during reward ( 28927378 ) Mean platelet volume ( 31194788 ) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095 ) Osteoporosis-related phenotypes ( 20548944 ) Platelet distribution width ( 32888494 ) Pursuit maintenance gain ( 29064472 ) Response to cytidine analogues (gemcitabine) ( 24483146 ) Skin aging (microtopography measurement) ( 28502801 )
Novel Interactors		None recorded	1 novel interactors: CD226
Interacting Genes		3 interacting genes: CRYBA1 CRYBA2 DOK6	20 interacting genes: ABHD11 ARID5A C1orf94 CRYBB3 EGFR ERBB2 FAM86C1P LASP1 LGALS14 METTL27 NTRK3 PRR22 RBPMS RET RUSC1 SLC30A6 TBX15 TLE5 USP54 YPEL3
Entrez ID		1417	220164
HPRD ID		00431	13244
Ensembl ID		ENSG00000100053	ENSG00000206052
Uniprot IDs		P26998	Q6PKX4
PDB IDs		3QK3	Not available
GO Terms Enriched among Interactors		Structural Constituent Of Eye Lens Lens Development In Camera-type Eye Visual Perception Sensory Perception Of Light Stimulus Positive Regulation Of Anoikis Sensory Perception Regulation Of Anoikis	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity ERBB2-EGFR Signaling Pathway Receptor Complex