BANF2 and CFP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BANF2	CFP
Description		BANF family member 2	complement factor properdin
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Nucleus Cytoplasm	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule Specific Granule Lumen Cytoplasmic Side Of Golgi Membrane Tertiary Granule Lumen
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Chromosome Organization	Immune System Process Immune Response Complement Activation Complement Activation, Alternative Pathway Defense Response To Bacterium Innate Immune Response Positive Regulation Of Complement Activation, Alternative Pathway Positive Regulation Of Immune Response Protein Stabilization Positive Regulation Of Opsonization
Pathways			Alternative complement activation Activation of C3 and C5 Defective B3GALTL causes PpS O-glycosylation of TSR domain-containing proteins Neutrophil degranulation Regulation of Complement cascade
Drugs
Diseases			Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS		Apolipoprotein B levels ( 32203549) Femur bone mineral density x serum urate levels interaction ( 34046847) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 30698716 32203549) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Low density lipoprotein cholesterol levels ( 33339817)
Interacting Genes		16 interacting genes: ADAMTSL4 BEND7 CFP CRX CRYBA1 DDIT4L DNAAF4 DUSP23 INCA1 KRTAP13-1 MTUS2 NTAQ1 PRDM6 PSMA1 SERTAD1 TCF4	33 interacting genes: BANF2 C3 CFAP206 CFB CYSRT1 FHL5 FKBP6 GEMIN4 GNE HEXIM2 HOXA1 KCTD9 KLHL38 KRTAP11-1 KRTAP12-2 KRTAP3-1 KRTAP6-2 LCE1A LONRF1 MID2 MTOR NEK6 NOXA1 PRKAB2 RECK SMARCC1 SPAG8 STK16 TRIP13 TXN VENTX ZNF330 ZNF414
Entrez ID		140836	5199
HPRD ID		12759	02308
Ensembl ID		ENSG00000125888	ENSG00000126759
Uniprot IDs		A0A140VK85 Q9H503	A0A0S2Z4I5 P27918
PDB IDs			1W0R 1W0S 6RUR 6RUS 6RUV 6RV6 6S08 6S0A 6S0B 6SEJ 7B26 7NOZ 8Q6R
Enriched GO Terms of Interacting Partners?
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