ASB11 and RPN1

Number of citations of the paper that reports this interaction (PMID 24337577)
0

Data Source:
BioGRID (enzymatic study)

		ASB11	RPN1
Gene Name		ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase	ribophorin I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Melanosome
	Molecular Function		Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction	Translation Cellular Protein Modification Process SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Translation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification SRP-dependent cotranslational protein targeting to membrane Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective MOGS causes MOGS-CDG (CDG-2b) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Defective ALG11 causes ALG11-CDG (CDG-1p)
Drugs
Diseases
GWAS			Monocyte count ( 23314186) White blood cell count ( 21738480)
Protein-Protein Interactions		3 interactors: CUL5 RPN1 UBC	13 interactors: ADRM1 ASB11 DPF1 ERBB3 HSPA5 RAD23A RBBP4 SGTA SIGIRR UBQLN1 UBQLN2 UBQLN4 WSB2
Entrez ID		140456	6184
HPRD ID		06450	01598
Ensembl ID		ENSG00000165192	ENSG00000163902
Uniprot IDs		Q7Z670 Q8WXH4	P04843
PDB IDs
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Apoptotic Signaling Pathway Negative Regulation Of Cell Cycle Ubiquitin-dependent Protein Catabolic Process Viral Protein Processing Modification-dependent Protein Catabolic Process Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Mitotic Cell Cycle Process Cellular Protein Modification Process Notch Receptor Processing Virion Assembly Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus Cellular Macromolecule Catabolic Process Membrane Organization Regulation Of Cell Cycle Apoptotic Process Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Programmed Cell Death Polysaccharide Biosynthetic Process Carbohydrate Metabolic Process Cell Cycle Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Death Death Negative Regulation Of ERBB Signaling Pathway Response To Abiotic Stimulus Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway	Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Folding In Endoplasmic Reticulum Cerebellum Structural Organization
Tagcloud ?			26s adopts atp atph coexisting commitment conformational conformations cryo dataset deconvolutes deubiquitylation em ensemble essentially executes gammas hydrolyzing interpretable landscape lid machine module move polyubiquitylated proteasome rendered static topology
Tagcloud (Difference) ?			26s adopts atp atph coexisting commitment conformational conformations cryo dataset deconvolutes deubiquitylation em ensemble essentially executes gammas hydrolyzing interpretable landscape lid machine module move polyubiquitylated proteasome rendered static topology
Tagcloud (Intersection) ?