TBC1D10C

Description		TBC1 domain family member 10C
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Filopodium Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Calcineurin-NFAT Signaling Cascade B Cell Activation Retrograde Transport, Endosome To Golgi Negative Regulation Of B Cell Activation ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Cilium Assembly
Pathways		Neutrophil degranulation TBC/RABGAPs
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		7 interacting genes: APP HOXA1 KLHL12 KRTAP13-1 KRTAP5-9 NOTCH2NLA PPP3R2
Entrez ID		374403
HPRD ID		13330
Ensembl ID		ENSG00000175463
Uniprot IDs		Q8IV04
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Visual Behavior Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Calcium-mediated Signaling Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Calcium-mediated Signaling Lipoprotein Particle Growth Factor Receptor Binding Main Axon Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior Intermediate Filament Sperm Mitochondrial Sheath Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Axon Choice Point Recognition Identical Protein Binding Heparan Sulfate Binding Signaling Receptor Activator Activity Embryonic Neurocranium Morphogenesis
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