FOXR2 and KRT76

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FOXR2	KRT76
Description		forkhead box R2	keratin 76
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Cytoskeleton Organization Epidermis Development Keratinization Pigmentation Intermediate Filament Organization Sebaceous Gland Development
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010)
Interacting Genes		5 interacting genes: CCNC KRT76 PEF1 POLR1C SUV39H1	47 interacting genes: AIRIM C1orf216 CAMK2A CCDC57 CDC37 CFAP206 DPPA3 EXOC8 FOXR2 FRS3 HGS IPO11 IQUB KIFC3 KRT13 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT75 KRT86 LCA5L LMO4 MID2 MTUS2 NFKBID POLR1C RSPH14 TNS2 TRIM23 TRIM27 TRIM54 TSGA10 WASHC1 ZNF655
Entrez ID		139628	51350
HPRD ID		13552	17123
Ensembl ID		ENSG00000189299	ENSG00000185069
Uniprot IDs		Q6PJQ5	Q01546
PDB IDs
Enriched GO Terms of Interacting Partners?		G0 To G1 Transition CKM Complex Histone H3K9 Trimethyltransferase Activity Histone H3K9me2 Methyltransferase Activity RDNA Heterochromatin Formation ENoSc Complex RDNA Heterochromatin Protein Dimerization Activity Sebaceous Gland Development Positive Regulation Of Protein Monoubiquitination Regulation Of Protein Monoubiquitination Neural Crest Formation Regulation Of Transcription By Glucose Histone H3K9 Methyltransferase Activity	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Organelle Organization Extracellular Exosome Anatomical Structure Morphogenesis Cell Differentiation Radial Spoke Hair Cycle Protein Binding Cellular Developmental Process Cytosol Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Structural Constituent Of Cytoskeleton Regulation Of Autophagy Developmental Process Epidermis Development Negative Regulation Of Viral Transcription Exocyst Keratinization Suppression Of Viral Release By Host Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Positive Regulation Of Autophagy Regulation Of Viral Transcription Actin Nucleation
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