HDX and BOLA2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HDX	BOLA2B
Description		highly divergent homeobox	bolA family member 2B
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Cytosol Iron-sulfur Cluster Assembly Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Protein Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation
Pathways			Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: BOLA1 BOLA2 BOLA2B CCDC57 CTNNA3 FHL5 GCC1 LMO1 LNX1 MID2 POLR1C RTN4IP1 SUFU TSGA10 TTC5 ZBTB16	32 interacting genes: ADAMTSL4 ANKRD55 BIRC2 BIRC7 C10orf55 C1orf94 CCDC138 CGGBP1 GLRX3 HDX ID3 IHO1 IL16 MBD3L1 MEOX2 MOBP NTAQ1 RAB4B RGS17 SLITRK5 TK1 TXNRD3 XIAP ZFP90 ZNF177 ZNF511 ZNF559-ZNF177 ZNF581 ZNF620 ZNF688 ZNF76 ZNF774
Entrez ID		139324	654483
HPRD ID		06550	19050
Ensembl ID		ENSG00000165259	ENSG00000169627
Uniprot IDs		Q7Z353	A0A499FJE1 Q9H3K6
PDB IDs		2DA4
Enriched GO Terms of Interacting Partners?		Iron-sulfur Cluster Assembly Complex Iron-sulfur Cluster Assembly Cell Redox Homeostasis Intracellular Iron Ion Homeostasis [2Fe-2S] Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding	Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Protein Polyubiquitination Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Polyubiquitination Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Metal Ion Binding Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Leptomycin B Leptomycin B Binding Regulation Of Transcription By RNA Polymerase II Pigment Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Natural Killer Cell Apoptotic Process
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