GLYCTK and ANKRD53

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GLYCTK	ANKRD53
Description		glycerate kinase	ankyrin repeat domain 53
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Cytosol	Spindle Pole Cytoplasm Spindle Cytoskeleton
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Glycerate Kinase Activity Kinase Activity Transferase Activity	Protein Binding
	Biological Process	Protein Phosphorylation Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate	Mitotic Metaphase Chromosome Alignment Positive Regulation Of Microtubule Polymerization Cell Division Regulation Of Mitotic Spindle Organization Regulation Of Mitotic Cytokinesis
Pathways		Fructose catabolism
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Hemoglobin levels ( 32327693) Schizophrenia ( 23974872 28991256)
Interacting Genes		59 interacting genes: ACTMAP ADAMTSL4 ANKRD53 ARMC5 ATP23 BAIAP2L2 CALCOCO2 CEP70 DTX2 EFHC2 GMPPB GOLGA2 IHO1 KLHL12 KRT13 KRT15 KRT19 KRT34 KRT75 KRTAP19-5 KRTAP6-2 KRTAP6-3 LZTS2 MAGED1 METTL15 METTL27 MGAT5B MIS18A MORN3 NFKBID NOTO NT5C2 PFDN5 PICK1 PLAGL2 POMC PRDM14 PUDP RBCK1 RBPMS REL SAXO1 SERTAD1 SMUG1 SNF8 SPAG8 SPRED1 STK33 TRIM27 TRIM42 TRIP13 TUBGCP4 UBP1 UFSP1 ZFP90 ZG16 ZIM2 ZNF620 ZNF688	3 interacting genes: BCL6 GLYCTK LZTR1
Entrez ID		132158	79998
HPRD ID		13586	07762
Ensembl ID		ENSG00000168237	ENSG00000144031
Uniprot IDs		C9JA32 Q8IVS8	C9JZ61 Q8N9V6
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Protein Binding Cytoskeleton Cytosol Axonemal Microtubule Supramolecular Fiber Organization Structural Molecule Activity	Negative Regulation Of Isotype Switching To IgE Isotypes Regulation Of Mitotic Cell Cycle DNA Replication Negative Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Mitotic Cell Cycle DNA Replication Negative Regulation Of Mast Cell Cytokine Production Isotype Switching To IgE Isotypes Negative Regulation Of Plasma Cell Differentiation Golgi Apparatus Intronic Transcription Regulatory Region Sequence-specific DNA Binding Fructose Catabolic Process Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Glycerate Kinase Activity Negative Regulation Of Isotype Switching Negative Regulation Of T-helper 2 Cell Differentiation Pyramidal Neuron Differentiation Regulation Of Small GTPase Mediated Signal Transduction Plasma Cell Differentiation Negative Regulation Of B Cell Differentiation Regulation Of Germinal Center Formation Paraspeckles T-helper 2 Cell Differentiation Type 2 Immune Response Germinal Center Formation Negative Regulation Of Immunoglobulin Production Negative Regulation Of DNA-templated DNA Replication Regulation Of Memory T Cell Differentiation Glyceraldehyde-3-phosphate Metabolic Process Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of B Cell Apoptotic Process Fructose Metabolic Process Negative Regulation Of Type 2 Immune Response Regulation Of B Cell Apoptotic Process Negative Regulation Of Rho Protein Signal Transduction Positive Regulation Of Regulatory T Cell Differentiation Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Negative Regulation Of DNA Replication Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of T-helper Cell Differentiation Isotype Switching Negative Regulation Of Cellular Senescence Negative Regulation Of Ras Protein Signal Transduction Somatic Diversification Of Immunoglobulins Involved In Immune Response Mature B Cell Differentiation Involved In Immune Response Replication Fork T-helper Cell Differentiation Negative Regulation Of Alpha-beta T Cell Differentiation Mature B Cell Differentiation B Cell Proliferation Regulation Of Isotype Switching Negative Regulation Of Cell-matrix Adhesion
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