GLYCTK and STK33

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		GLYCTK	STK33
Description		glycerate kinase	serine/threonine kinase 33
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Cytosol	Manchette Nucleus Cytoplasm Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Glycerate Kinase Activity Kinase Activity Transferase Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate	Spermatogenesis Cell Differentiation Mitotic DNA Damage Checkpoint Signaling Protein Autophosphorylation Manchette Assembly
Pathways		Fructose catabolism
Drugs			Fostamatinib
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Hemoglobin levels ( 32327693) Schizophrenia ( 23974872 28991256)	Adult body size ( 32376654) Body mass index ( 19079261 26426971 28448500 28892062) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Fruit consumption ( 32066663) Intake of total sugars ( 31005972) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Small cell lung carcinoma ( 28604730)
Interacting Genes		59 interacting genes: ACTMAP ADAMTSL4 ANKRD53 ARMC5 ATP23 BAIAP2L2 CALCOCO2 CEP70 DTX2 EFHC2 GMPPB GOLGA2 IHO1 KLHL12 KRT13 KRT15 KRT19 KRT34 KRT75 KRTAP19-5 KRTAP6-2 KRTAP6-3 LZTS2 MAGED1 METTL15 METTL27 MGAT5B MIS18A MORN3 NFKBID NOTO NT5C2 PFDN5 PICK1 PLAGL2 POMC PRDM14 PUDP RBCK1 RBPMS REL SAXO1 SERTAD1 SMUG1 SNF8 SPAG8 SPRED1 STK33 TRIM27 TRIM42 TRIP13 TUBGCP4 UBP1 UFSP1 ZFP90 ZG16 ZIM2 ZNF620 ZNF688	5 interacting genes: APP GLYCTK HPD USP15 USP5
Entrez ID		132158	65975
HPRD ID		13586	09642
Ensembl ID		ENSG00000168237	ENSG00000130413
Uniprot IDs		C9JA32 Q8IVS8	B3KS39 B4DDH2 F8WAK5 Q9BYT3
PDB IDs			8VF6
Enriched GO Terms of Interacting Partners?		Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Protein Binding Cytoskeleton Cytosol Axonemal Microtubule Supramolecular Fiber Organization Structural Molecule Activity	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Lysosome Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling 4-hydroxyphenylpyruvate Dioxygenase Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen Cysteine-type Deubiquitinase Activity Protein Deubiquitination Protein Modification By Small Protein Removal Cysteine-type Peptidase Activity Deubiquitinase Activity Regulation Protein Catabolic Process At Presynapse Cysteine-type Endopeptidase Activity GDP-L-fucose Biosynthetic Process Fucose-1-phosphate Guanylyltransferase Activity Negative Regulation Of Antifungal Innate Immune Response Protein K27-linked Deubiquitination Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Fructose Catabolic Process Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Glycerate Kinase Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway L-tyrosine Catabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?