DNAJC19 and CETN3

		DNAJC19	CETN3
Description		DnaJ heat shock protein family (Hsp40) member C19	centrin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Membrane Protein-containing Complex Inner Mitochondrial Membrane Protein Complex Matrix Side Of Mitochondrial Inner Membrane	Nucleus Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytoskeleton Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Nuclear Pore Nuclear Basket Transcription Export Complex 2
	Molecular Function	ATPase Activator Activity Protein Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	Protein Folding Protein Targeting To Mitochondrion Intracellular Protein Transport Visual Perception Protein Transport Protein Import Into Mitochondrial Matrix Genitalia Development Regulation Of Cardiolipin Metabolic Process	Microtubule Cytoskeleton Organization Centrosome Cycle Protein Transport MRNA Transport Cell Division
Pathways		Mitochondrial protein import
Drugs
Diseases		3-Methylglutaconic aciduria (MGCA)
GWAS		Schizophrenia ( 25056061 28991256 29483656 30285260)	Rosacea symptom severity ( 29771307) Serum alkaline phosphatase levels ( 33547301) Type 2 diabetes ( 19734900)
Interacting Genes		3 interacting genes: APP HSPA9 MCPH1	14 interacting genes: AGR2 CKMT2 HSPB1 IKBKG LDB2 LMNA LRIF1 LRRK2 MFHAS1 PDE6D RCN1 SGK1 TNNI1 UNC119
Entrez ID		131118	1070
HPRD ID		12349	04216
Ensembl ID		ENSG00000205981	ENSG00000153140
Uniprot IDs		A0A0S2Z5X1 Q96DA6	E5RFM2 E5RJF8 O15182
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway System Process Protein Folding Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Apoptotic Signaling Pathway Protein Folding Chaperone Negative Regulation Of Protein Kinase C Signaling Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Intracellular Protein Transport HSP90-CDC37 Chaperone Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Developmental Process DNA Double-strand Break Attachment To Nuclear Envelope Regulation Of System Process Structural Constituent Of Nuclear Lamina Visual Perception Sensory Perception Of Light Stimulus Regulation Of Catalytic Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Macrophage Activation Cellular Response To Curcumin Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Protein Localization To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly Cellular Response To Stress Mitochondrion Response To Unfolded Protein Regulation Of Locomotion Protein Transport Response To Heat Regulation Of Protein Modification Process Protein Kinase C Inhibitor Activity Ubiquitin Protein Ligase Binding Linear Polyubiquitin Binding
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