CIMIP5 and NRBP1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		CIMIP5	NRBP1
Name		ciliary microtubule inner protein 5	nuclear receptor binding protein 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Cell Projection	Nucleoplasm Cytoplasm Cell Cortex Endomembrane System Membrane Lamellipodium Cell Projection
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	None	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport DNA Damage Response
Pathways		None	Nuclear Receptor transcription pathway
GWAS		No GWAS studies recorded	Bone mineral density (total hip) ( 29883787 ) Creatinine levels ( 31015462 ) Crohn's disease ( 28067908 ) Hypertriglyceridemia ( 23505323 ) Inflammatory bowel disease ( 28067908 ) Takayasu arteritis ( 25604533 )
Novel Interactors		1 novel interactors: NOL10	None recorded
Interacting Genes		4 interacting genes: CFTR GSTA4 NRBP1 SPP1	17 interacting genes: BCL2L13 BTG3 CDKN1A CIMIP5 CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 SNX31 SORBS3 TIAM1 TK1 TSC22D4
Entrez ID		130813	29959
HPRD ID		08051	05819
Ensembl ID		ENSG00000150873	ENSG00000115216
Uniprot IDs		Q96LR7	F8W6G1 Q9UHY1
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Hormone Secretion Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Positive Regulation Of Enamel Mineralization Regulation Of Hormone Secretion Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Response To Ketone Transepithelial Water Transport Steroid Metabolic Process Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Androgen Catabolic Process Cellular Response To Testosterone Stimulus Response To 2,3,7,8-tetrachlorodibenzodioxine Amelogenesis Response To Macrophage Colony-stimulating Factor Positive Regulation Of Secretion By Cell ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Positive Regulation Of Secretion Epithelial Fluid Transport Positive Regulation Of Bone Resorption Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration Golgi-associated Vesicle Membrane Hormone Catabolic Process Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Cellular Response To Lipid Regulation Of Collateral Sprouting Decidualization Small Molecule Binding Steroid Catabolic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Water Transport Androgen Metabolic Process	Intracellular Signaling Cassette Wnt Signaling Pathway Regulation Of Dopaminergic Neuron Differentiation