ACMSD and GPSM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACMSD	GPSM3
Description		aminocarboxymuconate semialdehyde decarboxylase	G protein signaling modulator 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Plasma Membrane
	Molecular Function	Aminocarboxymuconate-semialdehyde Decarboxylase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Lyase Activity Carboxy-lyase Activity Metal Ion Binding	Protein Binding GTPase Regulator Activity
	Biological Process	L-tryptophan Catabolic Process Secondary Metabolic Process Negative Regulation Of Quinolinate Biosynthetic Process Picolinic Acid Biosynthetic Process Regulation Of 'de Novo' NAD Biosynthetic Process From L-tryptophan	Positive Regulation Of Leukocyte Chemotaxis Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		Tryptophan catabolism	G alpha (i) signalling events
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Diisocyanate-induced asthma ( 25918132) Free thyroxine concentration ( 30367059) Hand grip strength ( 29691431) Hematocrit ( 28017375) LDL cholesterol levels ( 32203549) Obesity-related traits ( 23251661) Parkinson's disease ( 21292315 25064009) Red blood cell count ( 32888494)	A body shape index ( 34021172) Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: GPSM3 MAGEA11 USHBP1	44 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KCNJ5-AS1 KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPMIP5 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 ZNF20 ZNF581
Entrez ID		130013	63940
HPRD ID		12326	13605
Ensembl ID		ENSG00000153086	ENSG00000213654
Uniprot IDs		A0A0S2Z681 Q6ZV40 Q8TDX5	A0A024RCP6 Q9Y4H4
PDB IDs		2WM1 4IGM 4IGN 4IH3 4OFC 7PWY
Enriched GO Terms of Interacting Partners?			Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex
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