BBS5 and KLHL23

		BBS5	KLHL23
Description		Bardet-Biedl syndrome 5	kelch like family member 23
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Axoneme Membrane Centriolar Satellite BBSome Ciliary Basal Body Cell Projection Ciliary Membrane	Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Heart Looping Visual Perception Protein Transport Cell Projection Organization Melanosome Transport Motile Cilium Assembly Intracellular Transport Cilium Assembly	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS		Iris heterochromicity ( 30895295)	Common carotid intima-media thickness in HIV infection ( 29206233) Obesity-related traits ( 23251661) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		4 interacting genes: CRADD KLC3 TOM1 TOM1L2	5 interacting genes: ANXA1 ANXA7 BNIP3L CDKN1A TK1
Entrez ID		129880	151230
HPRD ID		10353	11320
Ensembl ID		ENSG00000163093	ENSG00000213160
Uniprot IDs		A0A0S2Z626 Q8N3I7	Q8NBE8
PDB IDs		6XTB
Enriched GO Terms of Interacting Partners?			Epithelial Cell Differentiation Calcium-dependent Phospholipid Binding Keratinocyte Differentiation Phosphatidylserine Binding Vesicle Membrane Calcium-dependent Protein Binding Positive Regulation Of Programmed Cell Death Epidermal Cell Differentiation PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Thymidine Kinase Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of T-helper 2 Cell Differentiation Myoblast Migration Involved In Skeletal Muscle Regeneration Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Neutrophil Apoptotic Process Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Leukocyte Proliferation Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Cell-matrix Adhesion DNA Synthesis Involved In Mitotic DNA Replication Thymidine Biosynthetic Process Regulation Of Neutrophil Apoptotic Process Phospholipase A2 Inhibitor Activity Positive Regulation Of T-helper 1 Cell Differentiation Neutrophil Clearance Oncogene-induced Cell Senescence Stress-induced Premature Senescence Thymidine Metabolic Process BBSome
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?