NMS and NMUR1

Number of citations of the paper that reports this interaction (PMID 15635449)
17

Data Source:
HPRD (in vitro)

		NMS	NMUR1
Gene Name		neuromedin S	neuromedin U receptor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function		Neuromedin U Receptor Activity G-protein Coupled Receptor Activity Neuropeptide Receptor Activity
	Biological Process	Neuropeptide Signaling Pathway	Calcium Ion Transport Chloride Transport Smooth Muscle Contraction G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Neuropeptide Signaling Pathway Calcium-mediated Signaling Inositol Phosphate-mediated Signaling
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-Protein Interactions		1 interactors: NMUR1	2 interactors: NMS NMU
Entrez ID		129521	10316
HPRD ID		17638	16039
Ensembl ID		ENSG00000204640	ENSG00000171596
Uniprot IDs		Q5H8A3	Q9HB89
PDB IDs
Enriched GO Terms of Interacting Partners?		Inositol Phosphate-mediated Signaling Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Smooth Muscle Contraction Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Calcium-mediated Signaling Neuropeptide Signaling Pathway Chloride Transport Second-messenger-mediated Signaling Muscle Contraction Inorganic Anion Transport Muscle System Process Calcium Ion Transport	Neuropeptide Signaling Pathway Gastric Acid Secretion Photoperiodism Positive Regulation Of Smooth Muscle Contraction G-protein Coupled Receptor Signaling Pathway Eating Behavior Regulation Of Smooth Muscle Contraction Acid Secretion Sensory Perception Of Pain Feeding Behavior Positive Regulation Of Hormone Secretion Positive Regulation Of Synaptic Transmission Digestion Regulation Of Muscle Contraction
Tagcloud ?		3h acetylcholine albumin almost blocked bovine bsa chromatography column completely deae eif fold fraction fractionation guinea heat ic50 ileal inhibitory isoelectric longitudinal micrograms muscarinic partially pigs scopolamine soluble zn2
Tagcloud (Difference) ?		3h acetylcholine albumin almost blocked bovine bsa chromatography column completely deae eif fold fraction fractionation guinea heat ic50 ileal inhibitory isoelectric longitudinal micrograms muscarinic partially pigs scopolamine soluble zn2
Tagcloud (Intersection) ?