UHMK1 and TSGA10IP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UHMK1	TSGA10IP
Description		U2AF homology motif kinase 1	testis specific 10 interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Axon Dendrite Cytoplasm Neuronal Ribonucleoprotein Granule	Cytoskeleton Photoreceptor Connecting Cilium
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Ribonucleoprotein Complex Binding Protein Serine Kinase Activity	Protein Binding
	Biological Process	Peptidyl-serine Phosphorylation Neuron Projection Development Positive Regulation Of Translational Initiation Regulation Of Protein Export From Nucleus Regulation Of Cell Cycle	Cilium Organization
Pathways		Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs
Diseases
GWAS		Bone mineral density (femoral neck) ( 27424934) Bone mineral density (total hip) ( 27424934) Discordance in emotional problems in monozygotic twins ( 27043157) Takayasu arteritis ( 25604533)	Acne (severe) ( 24927181) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Severe influenza A (H1N1) infection ( 26379185) Urate levels ( 31578528)
Interacting Genes		9 interacting genes: AIRIM DEPDC1B LMO1 NDUFAF3 PAM RGS8 STMN1 TMSB4X TSGA10IP	112 interacting genes: AIRIM AKAP8L AMOTL2 AP1B1 ARHGEF9 BICD2 BICDL2 BIRC7 BRCA1 CALCOCO2 CARD9 CAVIN1 CBY2 CCDC102B CCDC120 CCDC125 CCDC13 CCDC136 CCDC57 CCDC88B CDKN2D CDR2 CDR2L CEP63 CEP70 CIB1 CRACR2B CTAG1A CTAG1B CYSRT1 DMAP1 DRC4 DYDC1 EFHC1 FCHSD2 FHL3 FRS3 FSD2 GOLGA2 GOLGA6A GOLGA6L9 GPRASP3 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF3 JAKMIP1 KANK2 KHDRBS3 KIFC3 KRT24 KRT36 KRT40 KRT86 KRTAP12-2 KRTAP6-2 LCA5L LDOC1 LIPE LMNB2 LMO2 LZTS1 MAGED1 MBD3L1 MDFI MEIS3 MEOX2 MIPOL1 MIS18A MKRN3 MSS51 MTUS2 NAB2 NCOA5 NUTM1 PARVG PDLIM7 PICK1 PRDM6 PRKAR1B PSTPIP1 RASGEF1B RBM4B RBPMS ROPN1 RORB RUNDC3A SAAL1 SORBS3 SPG21 SSX2IP STX11 STX1A TBC1D1 TEKT1 TFIP11 TLE5 TRAF2 TRAF4 TRIM27 TRIM5 TRIM50 TRIP6 TSC1 TTC23 TTC23L UHMK1 WWOX YES1 ZRANB1
Entrez ID		127933	254187
HPRD ID		12318	08147
Ensembl ID		ENSG00000152332	ENSG00000175513
Uniprot IDs		Q8TAS1	Q3SY00
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidylamidoglycolate Lyase Activity Peptidylglycine Monooxygenase Activity Fatty Acid Primary Amide Biosynthetic Process Actin Monomer Sequestering Activity Peptide Amidation Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Supramolecular Fiber Organization Regulation Of GTPase Activity Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity Regulation Of Catalytic Activity Negative Regulation Of Protein-containing Complex Assembly Regulation Of T Cell Homeostatic Proliferation Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Ascorbate As One Donor, And Incorporation Of One Atom Of Oxygen Positive Regulation Of Ligase Activity Negative Regulation Of Hematopoietic Stem Cell Differentiation	Identical Protein Binding Protein Binding Cytoskeleton Microtubule-based Process Cytoskeleton Organization Cytoplasm Centrosome Organelle Organization Intermediate Filament Golgi To Secretory Granule Transport Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Microtubule-based Movement Cytoskeleton-dependent Intracellular Transport
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