CNR1 and NSRP1

Number of citations of the paper that reports this interaction (PubMedID 26475744)
0

Data Source:
BioGRID (pull down)

		CNR1	NSRP1
Description		cannabinoid receptor 1	nuclear speckle splicing regulatory protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Plasma Membrane Actin Cytoskeleton Membrane Axon Growth Cone Presynaptic Membrane Cell Projection Membrane Raft Synapse Presynapse Glutamatergic Synapse GABA-ergic Synapse	Nucleus Nucleoplasm Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	G Protein-coupled Receptor Activity Cannabinoid Receptor Activity Protein Binding Identical Protein Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Axonal Fasciculation Cannabinoid Signaling Pathway Glucose Homeostasis Retrograde Trans-synaptic Signaling By Endocannabinoid Regulation Of Presynaptic Cytosolic Calcium Ion Concentration	Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing RNA Splicing Developmental Process
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events	mRNA Splicing - Major Pathway
Drugs		Dronabinol Nabilone Ricinoleic acid SLV319 V24343 AVE-1625 Rimonabant Cannabidiol Propacetamol Otenabant Tetrahydrocannabivarin Medical Cannabis Nabiximols
Diseases
GWAS		Depression in smokers ( 30219690) Gut microbiota (functional units) ( 27694959)	Brain morphology (MOSTest) ( 32665545) QRS complex (12-leadsum) ( 27659466)
Interacting Genes		10 interacting genes: ADORA2A BECN2 GNA15 GNAI1 GNAI2 GNAI3 HCRTR1 MET NSRP1 SSTR5	11 interacting genes: APP CNR1 CNRIP1 CTNNBL1 DISC1 FBXO25 NEDD4 NEDD4L RANBP9 SRPK1 SRPK2
Entrez ID		1268	84081
HPRD ID		00259	08536
Ensembl ID		ENSG00000118432	ENSG00000126653
Uniprot IDs		P21554 S5TLS4 V5KA96	A0A024QZ33 B7ZL27 Q9H0G5
PDB IDs		1LVQ 1LVR 2B0Y 2KOE 2MZ2 2MZ3 2MZA 5TGZ 5U09 5XR8 5XRA 6KPG 6KQI 6N4B 7FEE 7V3Z 7WV9 8GAG 8GHV 8IKG 8IKH 8K8J 8WRZ 8WU1 9B54 9B65 9B9Y 9B9Z 9BA0 9ERX
Enriched GO Terms of Interacting Partners?		Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Binding Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Adenosine Receptor Signaling Pathway Positive Regulation Of Urine Volume Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity GTPase Activity Neuropeptide Signaling Pathway GTP Binding Regulation Of Urine Volume G Protein-coupled Acetylcholine Receptor Signaling Pathway Purinergic Nucleotide Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Midbody Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Secretion By Cell Acetylcholine Receptor Signaling Pathway Regulation Of Secretion Postsynaptic Signal Transduction Regulation Of Protein Secretion Signal Transduction Regulation Of ERK1 And ERK2 Cascade Excitatory Postsynaptic Potential Hepatocyte Growth Factor Receptor Activity Plasma Membrane Ciliary Basal Body Regulation Of Cell Communication Regulation Of Signaling GDP Binding Feeding Behavior G Protein-coupled Receptor Activity Orexin Receptor Activity G Protein-coupled Receptor Catabolic Process Regulation Of Postsynaptic Membrane Potential Regulation Of Protein Transport Positive Regulation Of Acetylcholine Secretion, Neurotransmission Nucleotide Binding D2 Dopamine Receptor Binding Positive Regulation Of Relaxation Of Smooth Muscle G Protein-coupled Serotonin Receptor Binding Cell Division Positive Regulation Of MAPK Cascade Regulation Of Acetylcholine Secretion, Neurotransmission Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway	Presynapse Negative Regulation Of Potassium Ion Export Across Plasma Membrane Sodium Channel Inhibitor Activity Potassium Channel Inhibitor Activity Regulation Of Synapse Organization GABA-ergic Synapse Negative Regulation Of Sodium Ion Transport Regulation Of Potassium Ion Export Across Plasma Membrane Ubiquitin Ligase Complex Cytoplasm Receptor Catabolic Process Positive Regulation Of Protein Metabolic Process Enzyme Binding Negative Regulation Of Potassium Ion Transmembrane Transport Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Amyloid Precursor Protein Catabolic Process Neuron Projection Development Negative Regulation Of Potassium Ion Transport Positive Regulation Of Viral Genome Replication Neuromuscular Junction Development Positive Regulation Of Protein Catabolic Process Positive Regulation Of Catabolic Process Glutamatergic Synapse Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization Immune Response Regulation Of Amyloid Precursor Protein Catabolic Process Innate Immune Response Growth Cone Lamellipodium Regulation Of Cell Projection Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Neuron Recognition Cell Projection Organization Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Receptor Metabolic Process Ubiquitin-protein Transferase Activity Protein Monoubiquitination Formation Of Structure Involved In A Symbiotic Process Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Type 1 Cannabinoid Receptor Binding Protein Metabolic Process Regulation Of Monoatomic Ion Transmembrane Transport Neuron Cellular Homeostasis Regulation Of Dendrite Morphogenesis Positive Regulation Of Viral Process Regulation Of Potassium Ion Transmembrane Transport
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