SEPTIN12 and RSPH14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEPTIN12	RSPH14
Description		septin 12	radial spoke head 14 homolog
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GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Spindle Cytoskeleton Cilium Septin Ring Microtubule Cytoskeleton Midbody Septin Complex Motile Cilium Cell Division Site Cleavage Furrow Cell Projection Perinuclear Region Of Cytoplasm Sperm Annulus	Radial Spoke Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding GDP Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Molecular Adaptor Activity	Protein Binding
	Biological Process	Spermatogenesis Intracellular Protein Localization Cell Differentiation Cell Division Cytoskeleton-dependent Cytokinesis
Pathways
Drugs
Diseases
GWAS			Serum parathyroid hormone levels ( 27927781)
Interacting Genes		3 interacting genes: APP LINC00839 RSPH14	40 interacting genes: ABI2 AGAP1 ALS2CL AP1M1 AP2M1 BPIFA1 CCDC102B CDR2 CNTROB COG6 EPS8 FHL3 GABPB1 GOLGA2 JUP KASH5 KIFC3 KRT15 KRT31 KRT40 KRT75 KRT76 LZTS1 MNS1 PIBF1 POLR1C REL RPH3AL RSPH3 SEPTIN12 SMAD4 TCF4 TRAF2 TRIM27 TRIM50 TRIM69 TRIM7 VPS9D1 ZNF474 ZNF629
Entrez ID		124404	27156
HPRD ID		08061	16136
Ensembl ID		ENSG00000140623	ENSG00000100218
Uniprot IDs		A0A140VJU2 Q8IYM1	Q9UHP6
PDB IDs		6MQ9 6MQB 6MQK 6MQL	8J07
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding	Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Structural Molecule Activity Protein Binding Identical Protein Binding Zonula Adherens Sebaceous Gland Development Clathrin Adaptor Complex Centrosome Separation Positive Regulation Of Actin Nucleation Small GTPase Binding Innate Immune Response Epithelial Cell-cell Adhesion Clathrin Adaptor Activity
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