RLN3 and RXFP1

Number of citations of the paper that reports this interaction (PubMedID 15649866)
0

Data Source:
HPRD (in vivo, in vitro)

		RLN3	RXFP1
Description		relaxin 3	relaxin family peptide receptor 1
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GO Annotations	Cellular Component	Extracellular Region	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Binding Hormone Activity Protein Binding	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Hormone Binding Metal Ion Binding
	Biological Process	Signal Transduction	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Parturition Hormone-mediated Signaling Pathway Extracellular Matrix Organization Myofibroblast Differentiation Lung Connective Tissue Development Nipple Morphogenesis
Pathways		G alpha (s) signalling events G alpha (i) signalling events Relaxin receptors	G alpha (s) signalling events Relaxin receptors
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Acute lymphoblastic leukemia (childhood) ( 22076464) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		3 interacting genes: RXFP1 RXFP3 RXFP4	4 interacting genes: RLN1 RLN2 RLN3 SRPK2
Entrez ID		117579	59350
HPRD ID		06031	05975
Ensembl ID		ENSG00000171136	ENSG00000171509
Uniprot IDs		B2RU28 K7ENX1 Q8WXF3	A0A087WWV0 A0A0A0MT52 B3KV27 B4DGP2 E9PCA3 Q59H16 Q9HBX9
PDB IDs		2FHW 2K1V	2JM4 2M7P 7TMW
Enriched GO Terms of Interacting Partners?		Galanin Receptor Activity G Protein-coupled Receptor Activity Neuropeptide Signaling Pathway Nipple Morphogenesis G Protein-coupled Receptor Signaling Pathway Lung Connective Tissue Development Outer Dynein Arm Docking Complex Myofibroblast Differentiation Determination Of Heart Left/right Asymmetry Parturition Ciliary Rootlet Positive Regulation Of Feeding Behavior Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Cerebrospinal Fluid Circulation Hormone Binding Outer Dynein Arm Assembly Seminiferous Tubule Development Regulation Of Feeding Behavior Positive Regulation Of Behavior	Hormone Activity Female Pregnancy Nuclear Speck Organization R-loop Processing
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