RLN3 and RXFP3

Number of citations of the paper that reports this interaction (PubMedID 24615237)
0

Data Source:
BioGRID (pull down, unspecified method)

		RLN3	RXFP3
Description		relaxin 3	relaxin family peptide receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Binding Hormone Activity Protein Binding	G Protein-coupled Receptor Activity Galanin Receptor Activity
	Biological Process	Signal Transduction	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Cytokinesis
Pathways		G alpha (s) signalling events G alpha (i) signalling events Relaxin receptors	G alpha (i) signalling events Relaxin receptors
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: RXFP1 RXFP3 RXFP4	10 interacting genes: APP ENO1 GNAS HSP90B1 KATNB1 NCKIPSD RLN3 TMEM248 TTC19 YWHAE
Entrez ID		117579	51289
HPRD ID		06031	17979
Ensembl ID		ENSG00000171136	ENSG00000182631
Uniprot IDs		B2RU28 K7ENX1 Q8WXF3	Q9NSD7
PDB IDs		2FHW 2K1V
Enriched GO Terms of Interacting Partners?		Galanin Receptor Activity G Protein-coupled Receptor Activity Neuropeptide Signaling Pathway Nipple Morphogenesis G Protein-coupled Receptor Signaling Pathway Lung Connective Tissue Development Outer Dynein Arm Docking Complex Myofibroblast Differentiation Determination Of Heart Left/right Asymmetry Parturition Ciliary Rootlet Positive Regulation Of Feeding Behavior Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Cerebrospinal Fluid Circulation Hormone Binding Outer Dynein Arm Assembly Seminiferous Tubule Development Regulation Of Feeding Behavior Positive Regulation Of Behavior	Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor Signaling Pathway Cellular Response To Manganese Ion Response To Manganese Ion Cellular Response To Catecholamine Stimulus Response To Catecholamine Low-density Lipoprotein Particle Receptor Binding Midbody Positive Regulation Of ATP Metabolic Process Regulation Of System Process Protein Phosphatase Inhibitor Activity Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Regulation Of Multicellular Organism Growth Acetylcholine Receptor Activator Activity Regulation Of Defense Response Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process G Protein-coupled Receptor Binding Protein Heterodimerization Activity Lipoprotein Particle Positive Regulation Of Protein Import Mu-type Opioid Receptor Binding Actin Rod Assembly Regulation Of Heart Rate By Hormone ATPase Regulator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Immune Response Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Transport Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Protein Phosphatase Binding Melanosome Trans-Golgi Network Membrane Regulation Of Innate Immune Response Positive Regulation Of Cellular Component Organization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
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