SLC16A10 and FUNDC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC16A10	FUNDC2
Description		solute carrier family 16 member 10	FUN14 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Cell Junction	Nucleus Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	L-tyrosine Transmembrane Transporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Aromatic Amino Acid Transmembrane Transporter Activity L-phenylalanine Transmembrane Transporter Activity L-tryptophan Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Transmembrane Transporter Activity Carboxylic Acid Transmembrane Transporter Activity	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Amino Acid Transmembrane Transport Thyroid Hormone Generation Amino Acid Transport Aromatic Amino Acid Transport Phenylalanine Transport Tryptophan Transport Tyrosine Transport Transmembrane Transport Thyroid Hormone Transport Thyroid-stimulating Hormone Secretion Carboxylic Acid Transmembrane Transport	Autophagy Of Mitochondrion Regulation Of Platelet Activation Intracellular Triglyceride Homeostasis
Pathways		Amino acid transport across the plasma membrane
Drugs
Diseases
GWAS		Bisphosphonate-associated atypical femoral fracture ( 31006051) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolic traits ( 21886157) Metabolite levels ( 22286219 23823483) Refractive error ( 32231278) Serum metabolite levels ( 33031748) Tyrosine levels ( 31560688) Ulcerative colitis ( 28067908)
Interacting Genes		4 interacting genes: FUNDC2 INSIG2 RACGAP1 TMEM14B	40 interacting genes: AQP6 ARL13B ARL15 ASCC2 ATP13A2 CD79A CIDEB COX20 CRB3 CYB5R3 EBP EIF6 ERGIC3 EVI2B FAM209A FCER1G FGF14 GPR152 KCNJ6 KIR2DL3 MGST3 NACA NSF NUDT21 REEP4 RETREG3 RGS1 SAT1 SDR16C5 SLC10A6 SLC16A10 SLC66A2 SLC71A2 STOM SYT2 TMEM14B TMEM154 TMX2 TP53I3 USP13
Entrez ID		117247	65991
HPRD ID		09613	06586
Ensembl ID		ENSG00000112394	ENSG00000165775
Uniprot IDs		Q8TF71	Q9BWH2
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol-3,4,5-trisphosphate Binding Neural Precursor Cell Proliferation Centralspindlin Complex Actomyosin Contractile Ring Assembly SREBP-SCAP-Insig Complex SREBP-SCAP Complex Retention In Endoplasmic Reticulum Negative Regulation Of SREBP Signaling Pathway Sulfate Transmembrane Transport Spindle Midzone Assembly Lipid Binding Mitotic Spindle Midzone Assembly Regulation Of SREBP Signaling Pathway Maintenance Of Protein Localization In Endoplasmic Reticulum Cranial Suture Morphogenesis Response To Sterol Depletion SREBP Signaling Pathway Cellular Response To Sterol Depletion Intracellular Triglyceride Homeostasis Oxysterol Binding Cortical Actin Cytoskeleton Organization Flemming Body Regulation Of Attachment Of Spindle Microtubules To Kinetochore Alpha-tubulin Binding Gamma-tubulin Binding Positive Regulation Of Cytokinesis Cell Population Proliferation Beta-tubulin Binding Cytokinetic Process Spindle Midzone NLS-bearing Protein Import Into Nucleus Negative Regulation Of Steroid Metabolic Process Cholesterol Biosynthetic Process Middle Ear Morphogenesis Positive Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Fatty Acid Metabolic Process Craniofacial Suture Morphogenesis Negative Regulation Of Fatty Acid Biosynthetic Process Maintenance Of Protein Localization In Organelle Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Steroid Biosynthetic Process ER-nucleus Signaling Pathway Sterol Biosynthetic Process Positive Regulation Of Cholesterol Metabolic Process Positive Regulation Of Steroid Metabolic Process Protein Sequestering Activity Acylglycerol Homeostasis Triglyceride Homeostasis Porphyrin-containing Compound Metabolic Process Tetrapyrrole Biosynthetic Process	Membrane
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