ACAP3 and EIF6

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACAP3	EIF6
Gene Name		ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	eukaryotic translation initiation factor 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Lamin Filament Nucleoplasm Nucleolus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	ARF GTPase Activator Activity Zinc Ion Binding	Translation Initiation Factor Activity Protein Binding Ribosome Binding Ribosomal Large Subunit Binding
	Biological Process	Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity	Ribosomal Subunit Export From Nucleus Translational Initiation Mature Ribosome Assembly Ribosomal Large Subunit Biogenesis
Pathways
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		3 interactors: EIF6 SLC35G2 TAB1	38 interactors: ABCF1 ACAP3 ACTG1 AKT1S1 ALDH2 APP C4orf27 CLEC4G CRELD1 CSNK2B DHX58 EIF2AK2 ENOX1 FHL2 FUNDC2 GIT1 GNB2L1 HIP1 ITGB4 KIAA1377 LRIF1 MRPS31 OAS3 OFD1 OS9 PDHA1 PLK1 POLA2 PRKCB PSME1 RPL6 SEPT3 TK1 UPF3B USP33 WFS1 XRN2 ZBTB26
Entrez ID		116983	3692
HPRD ID		10820	04221
Ensembl ID		ENSG00000131584	ENSG00000242372
Uniprot IDs		Q8WTZ1 Q96P50	P56537
PDB IDs
Enriched GO Terms of Interacting Partners?		Mature Ribosome Assembly Activation Of MAPKKK Activity Ribosomal Subunit Export From Nucleus Ribosomal Large Subunit Biogenesis Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Ribosome Assembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway JNK Cascade	Positive Regulation Of Cellular Protein Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Proteolysis Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cell Cycle Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Proteolysis Regulation Of Translation Positive Regulation Of Peptidase Activity Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Signal Transduction Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Metabolic Process Cell Projection Morphogenesis Cell Projection Organization Response To Stress Cell Part Morphogenesis Gene Expression Axon Guidance Regulation Of Signaling Positive Regulation Of Catalytic Activity Mitotic Cell Cycle Process Regulation Of Binding Negative Regulation Of Defense Response To Virus Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Hydrolase Activity Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process Cell Morphogenesis Positive Regulation Of Metabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Phosphorylation Modification-dependent Protein Catabolic Process Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transferase Activity Axonogenesis Response To External Stimulus Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Innate Immune Response
Tagcloud ?			40s 60s 80s associates biogenesis cerevisiae cessation depleted designated encodes imbalance lysates maps mer monosomes mr polyribosomes polysomal prevents ribosomal ribosomes saccharomyces stoichiometric subunits tif6 true ultimately xvi yeast
Tagcloud (Difference) ?			40s 60s 80s associates biogenesis cerevisiae cessation depleted designated encodes imbalance lysates maps mer monosomes mr polyribosomes polysomal prevents ribosomal ribosomes saccharomyces stoichiometric subunits tif6 true ultimately xvi yeast
Tagcloud (Intersection) ?