EIF6 and MRPS31

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF6	MRPS31
Description		eukaryotic translation initiation factor 6	mitochondrial ribosomal protein S31
Image
GO Annotations	Cellular Component	Nucleus Lamin Filament Nucleoplasm Nucleolus Cytoplasm Cytosol Intermediate Filament Synapse Extracellular Exosome	Nucleolus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Translation Initiation Factor Activity Protein Binding Ribosome Binding Ribosomal Large Subunit Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Protein Domain Specific Binding
	Biological Process	Ribosomal Subunit Export From Nucleus Maturation Of 5.8S RRNA Maturation Of LSU-rRNA Regulation Of Glycolytic Process Translation Translational Initiation Response To Insulin MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Ribosome Biogenesis Cytosolic Ribosome Assembly Ribosomal Large Subunit Biogenesis Regulation Of Fatty Acid Biosynthetic Process Regulation Of Megakaryocyte Differentiation Positive Regulation Of Translation Assembly Of Large Subunit Precursor Of Preribosome Regulation Of Reactive Oxygen Species Metabolic Process	Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs		Copper
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Fish- and plant-related diet ( 32066663) Height ( 18391951) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Diastolic blood pressure ( 30224653) Keratoconus ( 33649486) Myeloproliferative neoplasms ( 33057200) Neutrophil percentage of granulocytes ( 27863252)
Interacting Genes		41 interacting genes: ABCF1 ACAP3 ACTG1 AKT1S1 ALDH2 APP CEP126 CLEC4G CRELD1 CSNK2B DHX58 EIF2AK2 ENOX1 FUNDC2 GIT1 HIP1 HPF1 ITGB4 LRIF1 MEOX2 MRPS31 MSRB3 OAS3 OFD1 OS9 PDHA1 PLK1 POLA2 PRKCB PSME1 PTEN RACK1 RPL6 SEPTIN3 TK1 UPF3B USP33 VAC14 WFS1 XRN2 ZBTB26	3 interacting genes: EIF6 LYST STAT3
Entrez ID		3692	10240
HPRD ID		04221	10098
Ensembl ID		ENSG00000242372	ENSG00000102738
Uniprot IDs		P56537	Q92665
PDB IDs		6LQM 6LSR 6LSS 6LU8 7OW7 8A3D 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL0 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8IDT 8IDY 8IE3 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8OHD 8OJ0 8OJ8 8RL2 9GMO	3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		Calyx Of Held Identical Protein Binding Regulation Of Proteolysis Regulation Of Translation Negative Regulation Of Gene Expression Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Viral Life Cycle Translation Anaphase-promoting Complex Binding Negative Regulation Of Cell Size Regulation Of Vesicle-mediated Transport Positive Regulation Of Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Viral Process Mitotic Nuclear Membrane Disassembly Centriolar Satellite Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Protein Binding Post-transcriptional Regulation Of Gene Expression Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Chemokine Production G Protein-coupled Receptor Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of Receptor Internalization Negative Regulation Of Viral Process Double-stranded RNA Binding Membrane Disassembly Spindle Organization Nuclear Membrane Disassembly Endoplasmic Reticulum Unfolded Protein Response Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Endocytosis Antiviral Innate Immune Response Postsynaptic Density Organization Negative Regulation Of Translation Protein Disulfide Isomerase Activity Ribosome	Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process Assembly Of Large Subunit Precursor Of Preribosome Regulation Of Generation Of Precursor Metabolites And Energy Mast Cell Secretory Granule Organization Intracellular Transport Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Regulation Of Myeloid Cell Differentiation Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Cellular Localization Establishment Of Localization In Cell Lamin Filament Nuclear Transport Nucleocytoplasmic Transport Cytosolic Ribosome Assembly RNA Sequestering Activity Postsynapse To Nucleus Signaling Pathway T-helper 17 Type Immune Response Response To Peptide Hormone Negative Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Interleukin-23-mediated Signaling Pathway Regulation Of Small Molecule Metabolic Process Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Interleukin-11-mediated Signaling Pathway Interleukin-9-mediated Signaling Pathway Cellular Response To Interleukin-17 Negative Regulation Of MiRNA Processing CCR5 Chemokine Receptor Binding Interleukin-10-mediated Signaling Pathway Cellular Response To Leptin Stimulus Positive Regulation Of Extracellular Matrix Disassembly Retinal Rod Cell Differentiation Interleukin-15-mediated Signaling Pathway Negative Regulation Of Inflammatory Response To Wounding Primary MiRNA Binding Leptin-mediated Signaling Pathway Regulation Of Hemopoiesis Ribosomal Subunit Export From Nucleus Negative Regulation Of Neuron Migration Ribosomal Large Subunit Binding Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of MiRNA Processing Growth Hormone Receptor Signaling Pathway Via JAK-STAT
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