DHRS1 and KRTAP12-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DHRS1	KRTAP12-1
Description		dehydrogenase/reductase 1	keratin associated protein 12-1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Carbonyl Reductase (NADPH) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Testosterone Dehydrogenase (NADP+) Activity Estradiol 17-alpha-dehydrogenase [NAD(P)+] Activity	Protein Binding
	Biological Process
Pathways			Keratinization
Drugs
Diseases
GWAS		Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		29 interacting genes: BNIP2 DIABLO HTR6 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP5-1 KRTAP5-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-8 LCE2B LHX4 MDFI MTUS2 NBPF19 NOTCH2NLA PLSCR1	62 interacting genes: CATSPER1 CHRD CYSRT1 DHRS1 ENKD1 FHL3 GATA3 GPRIN2 GRN HOXA1 HOXC8 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-2 KRTAP4-4 KRTAP4-5 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE3A LCE5A MEOX2 MGAT5B NBPF19 NEU4 NOTCH2NLA OTX1 PDIA2 PDIA4 PEF1 POU2AF1 POU4F2 PRR35 RBPMS SMCP TOX TRIP13 UBQLN2 VGLL3 ZIC1
Entrez ID		115817	353332
HPRD ID		09914	11197
Ensembl ID		ENSG00000157379	ENSG00000187175
Uniprot IDs		Q96LJ7	P59990
PDB IDs		2QQ5
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Cytosol Keratinization	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Protein Binding
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