C1QTNF1 and C1QTNF6

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		C1QTNF1	C1QTNF6
Description		C1q and TNF related 1	C1q and TNF related 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Plasma Membrane	Extracellular Region Collagen Trimer Extracellular Space Protein-containing Complex
	Molecular Function	Protein Binding Collagen Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Platelet Activation Positive Regulation Of Gene Expression Regulation Of Glucose Metabolic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Platelet Aggregation Positive Regulation Of Aldosterone Secretion
Pathways
Drugs
Diseases			Type I diabetes mellitus
GWAS			Autoimmune thyroid disease ( 32581359) Eosinophil percentage of white cells ( 32888494) Graves' disease ( 23612905) Hypothyroidism ( 22493691 27182965) Medication use (thyroid preparations) ( 31015401) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Systemic lupus erythematosus ( 28714469) Type 1 diabetes ( 18978792 19430480 25751624 30572963) Vitiligo ( 20410501 27723757)
Interacting Genes		11 interacting genes: AVPR2 C14orf119 C1QTNF6 CACNA1A LMNA LNX1 PRPF31 SGTA TGM1 UBL5 UBQLN4	3 interacting genes: C1QTNF1 SGTA SGTB
Entrez ID		114897	114904
HPRD ID		12714	12718
Ensembl ID		ENSG00000173918	ENSG00000133466
Uniprot IDs		A0A0C4DFP7 A0A3B0J271 Q9BXJ1	Q9BXI9
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding	TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To ER Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Protein Targeting Molecular Adaptor Activity Positive Regulation Of Aldosterone Secretion BAT3 Complex Binding Establishment Of Protein Localization To Organelle Negative Regulation Of ERAD Pathway Identical Protein Binding Negative Regulation Of Platelet Aggregation Negative Regulation Of Homotypic Cell-cell Adhesion Localization Within Membrane Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of ERAD Pathway Negative Regulation Of Platelet Activation Regulation Of ERAD Pathway Protein Heterooligomerization Protein Insertion Into ER Membrane Regulation Of Platelet Aggregation Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Response To Endoplasmic Reticulum Stress Hsp70 Protein Binding Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Negative Regulation Of Coagulation Regulation Of Platelet Activation Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Collagen Binding
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