TMEM200A and CNIH2

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		TMEM200A	CNIH2
Description		transmembrane protein 200A	cornichon family AMPA receptor auxiliary protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane ER To Golgi Transport Vesicle Membrane Postsynaptic Density Membrane Dendrite AMPA Glutamate Receptor Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cell Projection Dendritic Spine Dendritic Shaft Synapse Postsynaptic Membrane
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process		Vesicle-mediated Transport Synaptic Transmission, Glutamatergic Regulation Of AMPA Receptor Activity
Pathways			COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Colorectal cancer (calcium intake interaction) ( 25192705) Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244)	Bipolar disorder ( 21926972 31043756) Insomnia ( 32332799) Urate levels ( 31578528)
Interacting Genes		4 interacting genes: BCL2L10 CNIH2 EMD UNC119	8 interacting genes: CD53 CREB3L1 GORAB HIBADH SNCA TMEM14B TMEM200A TMPRSS2
Entrez ID		114801	254263
HPRD ID		13901	13078
Ensembl ID		ENSG00000164484	ENSG00000174871
Uniprot IDs		Q86VY9	Q6PI25
PDB IDs			8SS2 8SS3 8SS4 8SS6 8SS7 8SSA 8SSB
Enriched GO Terms of Interacting Partners?		Spindle TMEM240-body Negative Regulation Of Caveolin-mediated Endocytosis Cortical Endoplasmic Reticulum Nuclear Membrane Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Protein Tyrosine Kinase Activity Trans-synaptic Signaling Synaptic Signaling Chemical Synaptic Transmission Regulation Of AMPA Receptor Activity Endoplasmic Reticulum Regulation Of Transport Caspase Binding Spindle Pole Centrosome Lipoprotein Transport Regulation Of Clathrin-dependent Endocytosis Regulation Of Neurotransmitter Receptor Activity	Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission 3-hydroxyisobutyrate Dehydrogenase Activity
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