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CNIH2

Description cornichon family AMPA receptor auxiliary protein 2
Image
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • ER To Golgi Transport Vesicle Membrane
  • Postsynaptic Density
  • Membrane
  • Dendrite
  • AMPA Glutamate Receptor Complex
  • Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
  • Cell Projection
  • Dendritic Spine
  • Dendritic Shaft
  • Synapse
  • Postsynaptic Membrane
Molecular Function
  • Signaling Receptor Binding
  • Protein Binding
Biological Process
  • Vesicle-mediated Transport
  • Synaptic Transmission, Glutamatergic
  • Regulation Of AMPA Receptor Activity
Pathways
  • COPII-mediated vesicle transport
  • Cargo concentration in the ER
Drugs
Diseases
GWAS
  • Bipolar disorder ( 21926972 31043756)
  • Insomnia ( 32332799)
  • Urate levels ( 31578528)
Interacting Genes 8 interacting genes: CD53 CREB3L1 GORAB HIBADH SNCA TMEM14B TMEM200A TMPRSS2
Entrez ID 254263
HPRD ID 13078
Ensembl ID ENSG00000174871
Uniprot IDs Q6PI25
PDB IDs 8SS2 8SS3 8SS4 8SS6 8SS7 8SSA 8SSB
Enriched GO Terms of Interacting Partners?
  • Response To Desipramine
  • Negative Regulation Of Norepinephrine Uptake
  • Phospholipase D Inhibitor Activity
  • Positive Regulation Of SNARE Complex Assembly
  • Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
  • 3-hydroxyisobutyrate Dehydrogenase Activity
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