SDSL and TUBGCP4

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SDSL	TUBGCP4
Description		serine dehydratase like	tubulin gamma complex component 4
Image
GO Annotations	Cellular Component	Cytosol	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Microtubule Cytoskeleton Membrane Recycling Endosome
	Molecular Function	L-serine Ammonia-lyase Activity Threonine Deaminase Activity Glutamate Racemase Activity Lyase Activity Isomerase Activity Pyridoxal Phosphate Binding Identical Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Amino Acid Metabolic Process L-serine Catabolic Process Lipid Metabolic Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		Threonine catabolism Serine metabolism	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs		Pyridoxal phosphate
Diseases
GWAS		Body mass index ( 26426971)	Glycine levels ( 30837465) HDL cholesterol ( 30275531) Liver enzyme levels (alkaline phosphatase) ( 33972514) Triglycerides ( 30275531)
Interacting Genes		1 interacting genes: TUBGCP4	32 interacting genes: ADAMTSL4 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM
Entrez ID		113675	27229
HPRD ID		11542	10616
Ensembl ID		ENSG00000139410	ENSG00000137822
Uniprot IDs		Q96GA7	Q9UGJ1
PDB IDs		2RKB	3RIP 6V69 6V6S 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK
Enriched GO Terms of Interacting Partners?		Microtubule Minus-end Binding Gamma-tubulin Ring Complex Gamma-tubulin Complex Microtubule Nucleation Gamma-tubulin Binding Cytoplasmic Microtubule Organization Structural Constituent Of Cytoskeleton Microtubule Organizing Center Spindle Assembly Meiotic Cell Cycle Spindle Organization Mitotic Cell Cycle Recycling Endosome Spindle Pole Microtubule Cytoskeleton Membraneless Organelle Assembly Microtubule	Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Cytoskeleton Intermediate Filament Organization Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Identical Protein Binding Bergmann Glial Cell Differentiation Structural Constituent Of Skin Epidermis Scaffold Protein Binding Microtubule Astrocyte Development
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