RDH13 and PSKH1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RDH13	PSKH1
Description		retinol dehydrogenase 13	protein serine kinase H1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Membrane Nuclear Speck
	Molecular Function	Oxidoreductase Activity All-trans-retinol Dehydrogenase (NADP+) Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Lipid Metabolic Process Response To High Light Intensity Retina Layer Formation Eye Photoreceptor Cell Development Retinol Metabolic Process Retinal Metabolic Process	Determination Of Left/right Symmetry Heart Development
Pathways		RA biosynthesis pathway
Drugs		Vitamin A
Diseases
GWAS		Mean platelet volume ( 32888494) Platelet distribution width ( 32888494)	Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		4 interacting genes: CFTR CYP3A5 GADD45G PSKH1	3 interacting genes: CDC6 RDH13 SNTA1
Entrez ID		112724	5681
HPRD ID		17963	01511
Ensembl ID		ENSG00000160439	ENSG00000159792
Uniprot IDs		B3KVA3 Q8NBN7	P11801
PDB IDs
Enriched GO Terms of Interacting Partners?		Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Endoplasmic Reticulum Membrane Positive Regulation Of Tooth Mineralization Alcohol Metabolic Process Chloride Channel Inhibitor Activity Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Steroid Metabolic Process Chloride Channel Regulator Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Membrane Hyperpolarization Lipid Hydroxylation Testosterone 6-beta-hydroxylase Activity Estrogen 16-alpha-hydroxylase Activity Oxidative Demethylation Alkaloid Catabolic Process Aflatoxin Metabolic Process Estrogen 2-hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Amelogenesis Alkaloid Metabolic Process ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Endoplasmic Reticulum Demethylation Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Toxin Metabolic Process Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Regulation Of Hormone Levels Water Transport Bicarbonate Transport Retinoic Acid Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Xenobiotic Catabolic Process Positive Regulation Of P38MAPK Cascade Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process
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