HSPB2-C11orf52 and SNX18

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HSPB2-C11orf52	SNX18
Description		HSPB2-C11orf52 readthrough (NMD candidate)	sorting nexin 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Endosome Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function		Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Phosphatidylinositol Binding
	Biological Process		Mitotic Cell Cycle Mitotic Cytokinesis Endocytosis Positive Regulation Of Catabolic Process Protein Transport Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity Cell Division Plasma Membrane Tubulation Positive Regulation Of Autophagosome Assembly
Pathways			Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Immune response to smallpox vaccine (IL-6) ( 22542470)
Interacting Genes		20 interacting genes: A1CF BAG3 BEX2 BICRAL CEP19 ENKD1 HOXB9 KANK2 LMO1 LMO3 MISP PATZ1 POGZ PRR35 RFPL3 SNX18 TLX3 VEZF1 WWOX YPEL3	19 interacting genes: ABI2 CPSF7 CYSRT1 DPPA4 GABARAP GOLGA2 HSF2BP HSPB2 HSPB2-C11orf52 KHDRBS3 KRTAP1-1 KRTAP6-3 MAP1LC3B MDFI MSS51 PTPN21 SOS1 SOS2 ZBTB42
Entrez ID		100528019	112574
HPRD ID			15407
Ensembl ID		ENSG00000254445	ENSG00000178996
Uniprot IDs			Q96RF0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Ciliary Basal Body Organelle Assembly Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Orientation Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	Regulation Of Pro-B Cell Differentiation Regulation Of Lymphoid Progenitor Cell Differentiation Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding SH3 Domain Binding Regulation Of T Cell Differentiation In Thymus B Cell Homeostasis Macroautophagy Regulation Of Hematopoietic Progenitor Cell Differentiation
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