WIF1 and RPL37

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		WIF1	RPL37
Gene Name		WNT inhibitory factor 1	ribosomal protein L37
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region	Cytosol Cytosolic Large Ribosomal Subunit
	Molecular Function	Protein Binding	RNA Binding Structural Constituent Of Ribosome RRNA Binding Metal Ion Binding
	Biological Process	Signal Transduction Multicellular Organismal Development Wnt Signaling Pathway Positive Regulation Of Fat Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation negative regulation of TCF-dependent signaling by WNT ligand antagonists XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Hippocampal volume ( 22504421)
Protein-Protein Interactions		4 interactors: ICOS KRTAP10-3 KRTAP10-8 RPL37	5 interactors: APP POLR1B SQSTM1 TCF3 WIF1
Entrez ID		11197	6167
HPRD ID		05541	16047
Ensembl ID		ENSG00000156076
Uniprot IDs		Q9Y5W5	P61927
PDB IDs		2D3J 2YGN 2YGO 2YGP 2YGQ	3J3B
Enriched GO Terms of Interacting Partners?		T Cell Tolerance Induction Tolerance Induction	Nucleologenesis Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Developmental Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Signal Transduction Regulation Of Cell Cycle Phase Transition Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axial Mesoderm Morphogenesis Nucleolus Organization Regulation Of Signaling Wnt Signaling Pathway Immunoglobulin V(D)J Recombination Axon Choice Point Recognition Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Cycle Regulation Of Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Neuron Remodeling Axial Mesoderm Development B Cell Lineage Commitment Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Macroautophagy Peyer's Patch Development Posttranscriptional Regulation Of Gene Expression Natural Killer Cell Differentiation Cellular Copper Ion Homeostasis Response To External Stimulus Anterior/posterior Axis Specification, Embryo Regulation Of Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter RRNA Transcription Copper Ion Homeostasis Suckling Behavior Regulation Of Neuron Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Stem Cell Maintenance Termination Of RNA Polymerase I Transcription V(D)J Recombination Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Neuron Maturation
Tagcloud ?		aberrantly aom apcmin azoxymethane blt1 citrobacter coincided colonocytes crypt crypts deazaneplanocin dextran doi dss dznep epigenetically ezh2 f681y h3k27me3 hydroxamic knocked onc outbred paralleled polyps rodentium suberoylanilide swiss zeste	aforementioned bind biogenesis downregulate e3 ectopically employ flag ha ligase mdm2 mdmx nucleolus null p53 relevantly respective revealing ribosomal ribosome rps rps15 rps20 stabilization stabilize surveillance tagged ways
Tagcloud (Difference) ?		aberrantly aom apcmin azoxymethane blt1 citrobacter coincided colonocytes crypt crypts deazaneplanocin dextran doi dss dznep epigenetically ezh2 f681y h3k27me3 hydroxamic knocked onc outbred paralleled polyps rodentium suberoylanilide swiss zeste	aforementioned bind biogenesis downregulate e3 ectopically employ flag ha ligase mdm2 mdmx nucleolus null p53 relevantly respective revealing ribosomal ribosome rps rps15 rps20 stabilization stabilize surveillance tagged ways
Tagcloud (Intersection) ?