WIF1

Description		Wnt inhibitory factor 1
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GO Annotations	Cellular Component	Extracellular Region Cell Surface
	Molecular Function	Signaling Receptor Binding Protein Binding Wnt-protein Binding
	Biological Process	Signal Transduction Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Fat Cell Differentiation
Pathways		TCF dependent signaling in response to WNT Negative regulation of TCF-dependent signaling by WNT ligand antagonists
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Hippocampal fissure volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 22504421) Macular thickness ( 30535121) Post bronchodilator FEV1/FVC ratio ( 26634245) Subiculum volume ( 30279459) Total hippocampal volume ( 30279459)
Interacting Genes		10 interacting genes: AURKA CRADD CYSRT1 DYRK1A FGFR4 ICOS KRTAP10-3 KRTAP10-8 RB1CC1 RPL37
Entrez ID		11197
HPRD ID		05541
Ensembl ID		ENSG00000156076
Uniprot IDs		Q9Y5W5
PDB IDs		2D3J 2YGN 2YGO 2YGP 2YGQ
Enriched GO Terms of Interacting Partners?		Protein Autophosphorylation Regulation Of Signal Transduction By P53 Class Mediator Protein Serine/threonine/tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Histone H3T45 Kinase Activity Ribophagy
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