CD160 and NUP205

		CD160	NUP205
Description		CD160 molecule	nucleoporin 205
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Side Of Membrane	Nucleus Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Membrane Nuclear Periphery Nuclear Pore Inner Ring
	Molecular Function	Transmembrane Signaling Receptor Activity Signaling Receptor Binding Protein Binding Kinase Binding MHC Class I Protein Complex Binding MHC Class I Receptor Activity MHC Class Ib Receptor Activity Activating MHC Class I Receptor Activity	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Angiogenesis Positive Regulation Of Cytokine Production Adaptive Immune Response Immune System Process Mucosal Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Natural Killer Cell Cytokine Production Regulation Of Adaptive Immune Response Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Negative Regulation Of Angiogenesis T Cell Costimulation Positive Regulation Of Type II Interferon Production Positive Regulation Of Natural Killer Cell Degranulation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Gram-negative Bacterium Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Negative Regulation Of Adaptive Immune Memory Response Positive Regulation Of Endothelial Cell Apoptotic Process	Nucleocytoplasmic Transport Nuclear Pore Organization Protein Transport MRNA Transport Nuclear Pore Complex Assembly
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653)	Age at first sexual intercourse ( 34211149) Apolipoprotein A1 levels ( 32203549) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Meat-related diet ( 32066663) Paget's disease ( 21623375) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Red blood cell count ( 32888494) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: AGTRAP CMTM5 CMTM6 MAL2 MDM4 SYP THRA TNFRSF14	4 interacting genes: HOXC10 NUP35 NUP93 NUP98
Entrez ID		11126	23165
HPRD ID		06833	17653
Ensembl ID		ENSG00000117281	ENSG00000155561
Uniprot IDs		O95971 Q6FH89	Q92621
PDB IDs		6NG3 6NG9 6NGG 7MSG	5IJN 5IJO 7PER 7R5J 7R5K
Enriched GO Terms of Interacting Partners?			Nuclear Pore Organization Structural Constituent Of Nuclear Pore Nucleus Organization Nuclear Pore Import Into Nucleus MRNA Transport Protein Import Into Nucleus Nuclear Pore Complex Assembly Nuclear Pore Nuclear Basket RNA Transport Nuclear Periphery Protein Localization To Nucleus Pore Complex Assembly Nucleobase-containing Compound Transport Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Nuclear Membrane Establishment Of Protein Localization To Organelle RNA Export From Nucleus Telomere Tethering At Nuclear Periphery Intracellular Protein Transport Activating MHC Class I Receptor Activity Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Protein Localization To Organelle Nuclear Export Negative Regulation Of Adaptive Immune Memory Response Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Negative Regulation Of T Cell Costimulation Nuclear Pore Cytoplasmic Filaments MHC Class I Receptor Activity Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell MHC Class Ib Receptor Activity Nuclear Pore Central Transport Channel Spinal Cord Motor Neuron Cell Fate Specification Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery MHC Class I Protein Complex Binding Protein Transport Telomere Localization Positive Regulation Of Natural Killer Cell Cytokine Production Nuclear Pore Outer Ring Intracellular Transport Regulation Of Natural Killer Cell Cytokine Production Nuclear Inclusion Body Establishment Of Protein Localization Nuclear Body Protein-containing Complex Organization Positive Regulation Of Immune Response To Tumor Cell Cellular Localization
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