ATF7 and TAF12

Number of citations of the paper that reports this interaction (PMID 15735663)
11

Data Source:
HPRD (in vivo, in vitro)

		ATF7	TAF12
Gene Name		activating transcription factor 7	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Periphery	PCAF Complex Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enzyme Binding Sequence-specific DNA Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Viral Process	Chromatin Organization DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Histone H3 Acetylation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleic Acid-templated Transcription
Pathways			RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Chromatin organization HIV Infection HATs acetylate histones RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation Chromatin modifying enzymes RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Height ( 21998595 20189936)
Protein-Protein Interactions		16 interactors: ATF2 CCDC155 FAM9B FCER2 FOS MAPK9 MITD1 OCIAD1 PTP4A1 PTP4A2 TAF12 TAF4 TAOK3 TMEM239 URI1 YY1	22 interactors: ATF7 CPSF1 HIST3H3 NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		11016	6883
HPRD ID		06968	15981
Ensembl ID		ENSG00000170653	ENSG00000120656
Uniprot IDs		P17544	Q16514
PDB IDs			1H3O
Enriched GO Terms of Interacting Partners?		Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Transcription From RNA Polymerase II Promoter Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MAPK Cascade MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Signal Transduction By Phosphorylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Response To Stress Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Immune Response Cellular Response To UV Cell Cycle Transcription Elongation From RNA Polymerase II Promoter Chromosome Localization To Nuclear Envelope Involved In Synapsis Apoptotic Mitochondrial Changes Response To Light Stimulus Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To DNA Damage Stimulus Response To Lipid Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Immune Response DNA-templated Transcription, Elongation Positive Regulation Of Immune System Process Positive Regulation Of Transforming Growth Factor Beta2 Production Response To Prostaglandin F Cellular Response To Light Stimulus Mitotic DNA Damage Checkpoint Heterocycle Metabolic Process	DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Peptidyl-lysine Modification Protein Acetylation Positive Regulation Of Metabolic Process Metabolic Process Histone H3 Acetylation Histone Modification DNA-templated Transcription, Termination Regulation Of Cellular Process Chromatin Silencing At RDNA Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-amino Acid Modification Chromatin Modification Chromosome Organization Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter
Tagcloud ?		akap6 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf4 tafs tfiid
Tagcloud (Difference) ?		akap6 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf4 tafs tfiid
Tagcloud (Intersection) ?