ATF7

Description		activating transcription factor 7
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Enzyme Binding CAMP Response Element Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Pseudoephedrine
Diseases
GWAS		Basophil count ( 32888494) Electroencephalogram traits ( 25387704) Heel bone mineral density ( 30598549) Height ( 20189936 21998595 25429064 31562340) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		18 interacting genes: ATF2 FAM9B FCER2 FOS KASH5 MAPK9 MBD3 MITD1 OCIAD1 PTP4A1 PTP4A2 TAF12 TAF4 TAOK3 TMEM239 UBC URI1 YY1
Entrez ID		11016
HPRD ID		06968
Ensembl ID		ENSG00000170653
Uniprot IDs		P17544
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Transcription By RNA Polymerase II MRNA Transcription DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Abducens Nucleus Development Mitotic DNA Integrity Checkpoint Signaling Cellular Response To Anisomycin Growth Plate Cartilage Chondrocyte Differentiation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Chromatin Binding Nucleoplasm Positive Regulation Of Cardiac Muscle Myoblast Proliferation Facial Nucleus Development Histone H2B Acetyltransferase Activity Promoter-specific Chromatin Binding DNA Damage Response Hypoglossal Nucleus Development Positive Regulation Of Nucleobase-containing Compound Metabolic Process JNK Cascade Nucleus RNA Polymerase II-specific DNA-binding Transcription Factor Binding Cellular Response To Stress H4 Histone Acetyltransferase Complex Positive Regulation Of Transforming Growth Factor Beta2 Production Transcription By RNA Polymerase II Cellular Response To Chemical Stress Growth Plate Cartilage Chondrocyte Proliferation Positive Regulation Of RNA Metabolic Process Mitotic DNA Damage Checkpoint Signaling Cellular Response To Oxidative Stress Positive Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process MAPK Cascade B Cell Antigen Processing And Presentation Fc Receptor Signaling Pathway Low-affinity IgE Receptor Activity Fc Receptor-mediated Immune Complex Endocytosis Fc-epsilon Receptor Signaling Pathway Response To Prolactin Conditioned Taste Aversion Regulation Of MiRNA Transcription Medium-term Memory Cellular Response To Prolactin JUN Kinase Activity Protein Localization To Tricellular Tight Junction Regulation Of Cellular Response To Stress Transcription Factor TFTC Complex Transcription Factor TFIID Complex Transcription Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription Initiation
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