FERMT2 and FBLIM1

Number of citations of the paper that reports this interaction (PMID 12679033)
83

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		FERMT2	FBLIM1
Gene Name		fermitin family member 2	filamin binding LIM protein 1
Image
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Cell Cortex Cell Surface Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Lamellipodium Membrane I Band Filamentous Actin	Stress Fiber Cytosol Focal Adhesion Cell Cortex
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Zinc Ion Binding Filamin Binding
	Biological Process	Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Regulation Of Cell Shape Wnt Signaling Pathway Integrin Activation Cell Junction Assembly Substrate Adhesion-dependent Cell Spreading Focal Adhesion Assembly Protein Localization To Membrane	Regulation Of Cell Shape Single Organismal Cell-cell Adhesion Regulation Of Integrin Activation Cell Junction Assembly
Pathways		Cell junction organization Cell-extracellular matrix interactions	Cell junction organization Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Cardiac Troponin-T levels ( 23247143)
Protein-Protein Interactions		2 interactors: APP FBLIM1	6 interactors: CUTA FERMT2 FLNA FLNB HIST1H3A LMO3
Entrez ID		10979	54751
HPRD ID		06374	09669
Ensembl ID		ENSG00000073712	ENSG00000162458
Uniprot IDs		Q96AC1	Q8WUP2
PDB IDs		2LGX 2LKO 4F7H	2K9U 2W0P
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Regulation Of Integrin Activation Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Adhesion Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Component Assembly Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior	Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Maintenance Of Protein Location In Cell Protein Localization Maintenance Of Protein Location Maintenance Of Location In Cell Cell Junction Assembly Protein Complex Assembly DNA Replication-dependent Nucleosome Assembly Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cytoskeletal Anchoring At Plasma Membrane MRNA Transcription From RNA Polymerase II Promoter Integrin Activation DNA Methylation On Cytosine Cellular Protein Localization Protein Localization To Membrane MRNA Transcription Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Chromatin Silencing At RDNA Blood Coagulation Hemostasis Protein Localization To Cell Surface Mitotic Spindle Assembly Early Endosome To Late Endosome Transport Regulation Of Gene Silencing Actin Crosslink Formation Cytoplasmic Sequestering Of Protein Focal Adhesion Assembly Regulation Of Body Fluid Levels Cellular Component Assembly Chromatin Silencing Wound Healing Dopamine Receptor Signaling Pathway Actin Cytoskeleton Organization
Tagcloud ?		abca7 bin1 cass4 cd2ap cd33 celf1 chapter discoveries drb1 drb5 epha1 inpp5d mef2c ms4a4 ms4a6 nme8 picalm pld3 psen1 psen2 ptk2b rin3 slc24a4 sorl1 touch trem2 trip4 unsuspected zcwpw1
Tagcloud (Difference) ?		abca7 bin1 cass4 cd2ap cd33 celf1 chapter discoveries drb1 drb5 epha1 inpp5d mef2c ms4a4 ms4a6 nme8 picalm pld3 psen1 psen2 ptk2b rin3 slc24a4 sorl1 touch trem2 trip4 unsuspected zcwpw1
Tagcloud (Intersection) ?