STIP1 and FKBP4

Number of citations of the paper that reports this interaction (PMID 21170051)
21

Data Source:
BioGRID (pull down)

		STIP1	FKBP4
Gene Name		stress-induced phosphoprotein 1	FK506 binding protein 4, 59kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Golgi Apparatus	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Microtubule Neuronal Cell Body Axonal Growth Cone Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding ATP Binding GTP Binding FK506 Binding Protein Binding, Bridging Heat Shock Protein Binding Copper-dependent Protein Binding Glucocorticoid Receptor Binding Poly(A) RNA Binding Tau Protein Binding Phosphoprotein Binding
	Biological Process	Response To Stress	Protein Peptidyl-prolyl Isomerization Protein Folding Steroid Hormone Receptor Complex Assembly Copper Ion Transport Embryo Implantation Negative Regulation Of Neuron Projection Development Androgen Receptor Signaling Pathway Prostate Gland Development Negative Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Protein Complex Localization Cellular Response To Heat Male Sex Differentiation Chaperone-mediated Protein Folding Regulation Of Cellular Response To Heat
Pathways			HSF1-dependent transactivation Attenuation phase Cellular response to heat stress
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 21784300)	Quantitative traits ( 19197348)
Protein-Protein Interactions		18 interactors: ACD AIP APP CDC37 EGFR FKBP4 FKBP5 HSP90AA1 HSPA14 HSPA1A HSPA4 HSPA8 LMO2 MAP3K8 POT1 PRNP PTGES3 SUMO4	25 interactors: ACVR1 ATOX1 CALM1 CSNK2A1 EGFR ESR1 FES FKBP1A GLMN HSF1 HSP90AA1 HSPA4 IRF4 NR3C1 NR3C2 PHYH PTPN2 S100A1 S100A2 S100A6 SH3BP4 SMURF2 SNCA SQSTM1 STIP1
Entrez ID		10963	2288
HPRD ID		05454	11794
Ensembl ID		ENSG00000168439
Uniprot IDs		P31948	Q02790
PDB IDs		1ELR 1ELW 2LNI 3ESK 3FWV	1N1A 1P5Q 1Q1C 1QZ2 4DRJ 4LAV 4LAW 4LAX
Enriched GO Terms of Interacting Partners?		Protein Folding Regulation Of Cellular Response To Heat Protein Refolding Cellular Response To Heat Response To Heat Chaperone-mediated Protein Folding Response To Temperature Stimulus Cellular Protein Metabolic Process Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Axon Guidance Response To Abiotic Stimulus Positive Regulation Of Telomerase Activity Protein Metabolic Process Protein Targeting To Mitochondrion Positive Regulation Of DNA Replication Telomere Maintenance Protein Localization To Mitochondrion Negative Regulation Of Telomere Maintenance Regulation Of Immune System Process Regulation Of Telomere Maintenance Via Telomerase Axonogenesis Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Chaperone-mediated Protein Complex Assembly Axon Development Response To Stress Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Telomerase Activity Chemotaxis Cellular Metabolic Process Intracellular Transport Neuron Projection Morphogenesis Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA Replication RNA-dependent DNA Replication Copper Ion Homeostasis Cell Morphogenesis Involved In Differentiation Regulation Of Catalytic Activity Positive Regulation Of DNA Metabolic Process Cellular Localization Mitochondrial Transport Locomotion Response To Oxidative Stress Protein Targeting	Response To Organic Substance Cellular Response To Organic Substance Regulation Of Oxidoreductase Activity Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Regulation Of Nitric-oxide Synthase Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Stimulus Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Response To Lipid Cellular Response To Growth Factor Stimulus Negative Regulation Of Signaling Response To Organic Cyclic Compound Response To Growth Factor Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Developmental Process System Development Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Cyclic Compound Signaling Regulation Of Signaling Regulation Of Immune System Process Cell Communication Defense Response Protein Import Into Mitochondrial Outer Membrane Response To Steroid Hormone Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Oxidoreductase Activity Response To Stress Regulation Of Cell Proliferation Positive Regulation Of Nitric Oxide Biosynthetic Process Multicellular Organismal Development Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Innate Immune Response Cellular Response To Glucocorticoid Stimulus Response To Glucocorticoid Anatomical Structure Development Cellular Response To Corticosteroid Stimulus Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Regulation Of Immune Response Response To Corticosteroid
Tagcloud ?		amongst chaperones chaperoning depleted dnaja1 dnajb1 dnajb6 dnajb8 dnhsf1 glucocorticoid hsf1 hsp90 hsp90aa1 hspa1a hspa6 hspb1 hspb8 limiting machines maintains p23 proteostasis proteotoxic ptges3 rescued severely st13 stressed transcriptomes
Tagcloud (Difference) ?		amongst chaperones chaperoning depleted dnaja1 dnajb1 dnajb6 dnajb8 dnhsf1 glucocorticoid hsf1 hsp90 hsp90aa1 hspa1a hspa6 hspb1 hspb8 limiting machines maintains p23 proteostasis proteotoxic ptges3 rescued severely st13 stressed transcriptomes
Tagcloud (Intersection) ?