RAB10 and GPN1

		RAB10	GPN1
Description		RAB10, member RAS oncogene family	GPN-loop GTPase 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Exocyst Cytoplasm Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Endosome Membrane Membrane Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Cell Projection Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network Secretory Vesicle	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Axonogenesis Protein Transport Vesicle-mediated Transport Endosomal Transport Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Glycated hemoglobin levels ( 34059833) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 27863252 32888494) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000) Platelet distribution width ( 32888494)	Bipolar disorder ( 31043756) Fasting blood glucose adjusted for BMI ( 25625282) Nonalcoholic fatty liver disease ( 29385134) Oral cavity cancer ( 27749845) Periodontitis (CDC/AAP) ( 24024966) Schizophrenia ( 26198764)
Interacting Genes		10 interacting genes: APP CEBPA ENOPH1 EVI5L MICAL1 MTNR1A PPBP RABIF RIMS1 SEPTIN9	5 interacting genes: CSNK2A1 MBD2 RPAP1 XPA ZBED1
Entrez ID		10890	11321
HPRD ID		06692	10308
Ensembl ID		ENSG00000084733	ENSG00000198522
Uniprot IDs		P61026	Q53RZ9 Q9HCN4
PDB IDs		5LPN 5SZJ
Enriched GO Terms of Interacting Partners?			Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Wnt Signaling Pathway PML Body Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair Factor 1 Complex Cellular Response To Serotonin Protein Autosumoylation Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Satellite DNA Binding Positive Regulation Of Aggrephagy Response To Bisphenol A Insulin-responsive Compartment
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