ZBTB6 and ZNF250

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB6	ZNF250
Description		zinc finger and BTB domain containing 6	zinc finger protein 250
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)	Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		10 interacting genes: ATF7IP FAM9A PLEKHF2 RNF4 SKIL SUMO1 SUMO1P1 ZBTB26 ZBTB48 ZNF250	110 interacting genes: ANKRD50 APOBEC3C BEGAIN CARD10 CARD9 CBY2 CCDC102B CCDC125 CCDC136 CCDC6 CCDC85B CDCA7L CDR2 CDR2L CEP44 CEP63 CEP70 DPPA2 DRC3 DRC4 DVL2 FAM124A FAM161A FDXACB1 FHL5 GMCL1 GMNN GNPTAB GOLGA2 GOLGA6L9 GRAP2 GRIPAP1 GUCD1 HEXIM2 HMBOX1 HOMEZ HOOK1 HOOK2 HSF2BP KASH5 KIFC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP4-12 LDOC1 LMO2 LZTS1 LZTS2 MAGOHB MEOX2 MID2 MTUS2 MYF5 NDEL1 NEXN NINL NXF1 PIBF1 PICK1 PLEKHF2 PRDM14 PRPF31 RUBCN RUNDC3A SPECC1L SPRED2 SSX2IP STX1A SYNE4 TFF1 TMCC2 TNK1 TNNT1 TNS2 TOP3B TRAF1 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A YJU2B ZBTB43 ZBTB6 ZBTB8A ZC4H2 ZCCHC13 ZCCHC7 ZFP1 ZNF165 ZNF175 ZNF202 ZNF330 ZNF345 ZNF460 ZNF473 ZNF547 ZNF57 ZNF572 ZNF639 ZNF648 ZNF668 ZNF768 ZNF792 ZNF837 ZRANB1
Entrez ID		10773	58500
HPRD ID		09341	15758
Ensembl ID		ENSG00000186130	ENSG00000196150
Uniprot IDs		Q15916	B3KNS9 P15622
PDB IDs
Enriched GO Terms of Interacting Partners?		PML Body PML Body Organization Protein Tag Activity Nuclear Body Organization Transcription Factor Binding Regulation Of Transcription By RNA Polymerase II Ubiquitin-like Protein Ligase Binding Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Sumoylation Regulation Of RNA Metabolic Process Nucleus Nuclear Body Nucleus Organization Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Kinetochore Assembly Negative Regulation Of Transcription By RNA Polymerase II Protein Localization To Nuclear Pore Zinc Ion Binding SUMO Polymer Binding Negative Regulation Of Action Potential Small Protein Activating Enzyme Binding	Protein Binding Zinc Ion Binding Identical Protein Binding Microtubule Binding Cytoskeleton Microtubule Regulation Of RNA Biosynthetic Process Centrosome Keratin Filament Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Metal Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Microtubule-based Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Response To Muramyl Dipeptide CBM Complex FHF Complex Cytoskeleton Organization Intermediate Filament
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