MTX2 and MTX1

Number of citations of the paper that reports this interaction (PMID 10381257)
14

Data Source:
HPRD (two hybrid, in vitro)

		MTX2	MTX1
Gene Name		metaxin 2	metaxin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane	Mitochondrial Outer Membrane Integral Component Of Membrane
	Molecular Function
	Biological Process	Protein Targeting To Mitochondrion Mitochondrial Transport Cellular Protein Metabolic Process	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process
Pathways		Mitochondrial protein import	Mitochondrial protein import
Drugs
Diseases
GWAS			Renal function-related traits (BUN) ( 22797727)
Protein-Protein Interactions		3 interactors: CCDC155 MTX1 TADA2A	3 interactors: CLN8 MTX2 TOMM40
Entrez ID		10651	4580
HPRD ID		09777	11861
Ensembl ID		ENSG00000128654	ENSG00000173171
Uniprot IDs		O75431	Q13505
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Tubulin Deacetylation	Mitochondrion Organization Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport L-glutamate Uptake Involved In Synaptic Transmission Establishment Of Protein Localization To Organelle Age-dependent Response To Oxidative Stress Somatic Motor Neuron Differentiation Protein Targeting L-glutamate Import Protein Localization To Organelle Neurotransmitter Uptake Neurofilament Cytoskeleton Organization Neuromuscular Process Controlling Posture Amino Acid Import Organelle Organization Cytoplasmic Transport L-glutamate Transport Photoreceptor Cell Maintenance Intracellular Protein Transport Intermediate Filament Cytoskeleton Organization Social Behavior Intermediate Filament-based Process Musculoskeletal Movement Spinal Cord Motor Neuron Differentiation Adult Walking Behavior Ceramide Biosynthetic Process Cellular Protein Metabolic Process Lysosome Organization Ventral Spinal Cord Development Protein Transmembrane Transport Retina Homeostasis Mitochondrial Membrane Organization Cell Differentiation In Spinal Cord Transport Cellular Protein Localization Sphingolipid Biosynthetic Process Neuromuscular Process Controlling Balance Protein Transport Dicarboxylic Acid Transport Associative Learning Establishment Of Protein Localization Ceramide Metabolic Process Intracellular Transport Protein Metabolic Process Vacuole Organization Spinal Cord Development Cholesterol Metabolic Process Adult Locomotory Behavior Ion Transport
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