MTX1

Description		metaxin 1
Image		No pdb structure
GO Annotations	Cellular Component	SAM Complex Mitochondrion Mitochondrial Outer Membrane Membrane MIB Complex
	Molecular Function	Protein Binding
	Biological Process	Mitochondrion Organization Inner Mitochondrial Membrane Organization Lactation Protein Transport Protein Insertion Into Mitochondrial Outer Membrane
Pathways		Mitochondrial protein import Cristae formation RAC2 GTPase cycle
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31451708 31015462) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric cancer ( 26098866) General risk tolerance (MTAG) ( 30643258) Gout ( 33832965) Hematocrit ( 27863252 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Red blood cell count ( 27863252 32888494) Renal function-related traits (BUN) ( 22797727) Serum cancer antigen 15.3 levels ( 31666285) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528) Urea levels ( 28270201)
Interacting Genes		7 interacting genes: A1BG CLN8 GABARAP MAP1LC3A MAP1LC3B MTX2 TOMM40
Entrez ID		4580
HPRD ID		11861
Ensembl ID		ENSG00000173171
Uniprot IDs		Q13505
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Vacuole Organization Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome Ceramide Binding Autophagosome Assembly Autophagosome Organization Mitochondrial Membrane Organization Protein Insertion Into Mitochondrial Outer Membrane Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Cellular Response To Starvation Organelle Organization Protein Insertion Into Mitochondrial Membrane Establishment Of Protein Localization To Mitochondrial Membrane Response To Starvation Mitochondrion Organization Microtubule Binding Cellular Response To Nutrient Levels Endomembrane System Organelle Membrane Autophagy Ubiquitin Protein Ligase Binding Microtubule Protein Insertion Into Membrane Establishment Of Protein Localization To Mitochondrion Response To Nutrient Levels Somatic Motor Neuron Differentiation Glutamate Reuptake Retinal Rod Cell Apoptotic Process Axoneme Positive Regulation Of Protein K48-linked Ubiquitination Cellular Response To Oxygen-glucose Deprivation Membrane Organization Mitochondrion Organelle Assembly Porin Activity Regulation Of Protein K48-linked Ubiquitination Retinal Cell Apoptotic Process Protein Targeting TOM Complex Mitochondrial Outer Membrane Response To Iron(II) Ion Establishment Of Protein Localization To Membrane Mitochondrial Outer Membrane Translocase Complex
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