NUP133 and NUP107

Number of citations of the paper that reports this interaction (PMID 11564755)
96

Data Source:
HPRD (in vitro, in vivo)

		NUP133	NUP107
Gene Name		nucleoporin 133kDa	nucleoporin 107kDa
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Condensed Chromosome Outer Kinetochore Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Centrosome Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery
	Molecular Function	Nucleocytoplasmic Transporter Activity Protein Binding	Nucleocytoplasmic Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Nuclear Pore Organization Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Paraxial Mesoderm Development Transmembrane Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Nuclear Pore Complex Assembly Transmembrane Transport
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase	Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS			White blood cell count ( 20139978)
Protein-Protein Interactions		3 interactors: CENPF NUP107 NUP98	2 interactors: NUP133 NUP214
Entrez ID		55746	57122
HPRD ID		06354	06356
Ensembl ID		ENSG00000069248	ENSG00000111581
Uniprot IDs		Q8WUM0	B4DZ67 P57740
PDB IDs		1XKS 3CQC 3CQG 3I4R	3CQC 3CQG 3I4R
Enriched GO Terms of Interacting Partners?		Nuclear Pore Complex Assembly Nuclear Pore Organization Pore Complex Assembly Cellular Protein Complex Assembly Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Cellular Macromolecular Complex Assembly Nuclear Envelope Organization Mitotic Cell Cycle Process Glucose Transport Hexose Transport Mitotic Cell Cycle Viral Transcription Regulation Of Glucose Transport MRNA Transport Nucleus Organization Carbohydrate Transport Protein Complex Assembly Cell Cycle Process RNA Transport RNA Localization Cell Cycle Viral Life Cycle Protein Transport Pathogenesis Protein Import Into Nucleus, Docking Establishment Of Protein Localization Nucleocytoplasmic Transport Nuclear Transport Cellular Component Assembly Protein Localization Establishment Of Localization In Cell Endomembrane System Organization Cytokine-mediated Signaling Pathway Cellular Localization Viral Process Cellular Response To Cytokine Stimulus Organelle Organization Cytoplasmic Transport Response To Cytokine Kinetochore Assembly Kinetochore Organization Membrane Organization Macromolecule Biosynthetic Process Metaphase Plate Congression Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Establishment Of Chromosome Localization	Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly MRNA Export From Nucleus Nuclear Envelope Organization Glucose Transport RNA Export From Nucleus Hexose Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export MRNA Transport Nucleus Organization Carbohydrate Transport RNA Transport RNA Localization Viral Life Cycle Pathogenesis Nucleocytoplasmic Transport Nuclear Transport Endomembrane System Organization Cytokine-mediated Signaling Pathway Viral Process Cellular Response To Cytokine Stimulus Nuclear Pore Organization Mitotic Cell Cycle Process Cytoplasmic Transport Response To Cytokine Mitotic Cell Cycle Membrane Organization Carbohydrate Metabolic Process Cell Cycle Process Paraxial Mesoderm Development Protein Export From Nucleus Cell Cycle Protein Transport Establishment Of Protein Localization Intracellular Transport Transmembrane Transport Cellular Response To Organic Substance Protein Localization Establishment Of Localization In Cell Small Molecule Metabolic Process Protein Import Into Nucleus Nuclear Import RNA Biosynthetic Process Cellular Localization Response To Organic Substance Mesoderm Development Protein Import Protein Localization To Nucleus
Tagcloud ?		anchored anchoring asun asunder bicaudal bicd2 cenp centromere centrosome coimmunoprecipitation conservation coupling dynein flies g2 germline lis1 lissencephaly meiosis motors multinucleation perinuclear pore prophase ranbp2 rescues spermatocytes spindles uncoupling	apparatus brefeldin coat contributions copii defects differentiate digestive disrupt disrupted excessive facilitates lamination npc nucleo oligonucleotide organ organogenesis phenocopied pore pores retina retinal sec13 sec31a sec31b sq198 surprisingly traffic
Tagcloud (Difference) ?		anchored anchoring asun asunder bicaudal bicd2 cenp centromere centrosome coimmunoprecipitation conservation coupling dynein flies g2 germline lis1 lissencephaly meiosis motors multinucleation perinuclear prophase ranbp2 rescues spermatocytes spindles uncoupling	apparatus brefeldin coat contributions copii defects differentiate digestive disrupt disrupted excessive facilitates lamination npc nucleo oligonucleotide organ organogenesis phenocopied pores retina retinal sec13 sec31a sec31b sq198 surprisingly traffic
Tagcloud (Intersection) ?		pore