SLC34A2 and FXYD6-FXYD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC34A2	FXYD6-FXYD2
Description		solute carrier family 34 member 2	FXYD6-FXYD2 readthrough
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Membrane Apical Plasma Membrane Brush Border Membrane Vesicle
	Molecular Function	Sodium:phosphate Symporter Activity Protein Binding Symporter Activity Sodium Ion Binding Phosphate Ion Binding
	Biological Process	In Utero Embryonic Development Monoatomic Ion Transport Sodium Ion Transport Phosphate Ion Transport Intracellular Phosphate Ion Homeostasis Sodium Ion Transmembrane Transport Response To Estrogen Sodium-dependent Phosphate Transport Transmembrane Transport
Pathways		Type II Na+/Pi cotransporters Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) Surfactant metabolism Defective SLC34A2 causes PALM
Drugs
Diseases		Non-small cell lung cancer
GWAS		Metabolite levels ( 23823483)	Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		19 interacting genes: AIG1 ERG28 FXYD6-FXYD2 GUCA2A JAGN1 LHFPL5 PLN PNLIPRP1 RTP2 SLC30A3 SLC35A1 SLC39A7 STRIT1 TEX264 TMEM128 TMEM239 TMEM42 TRARG1 TSPO2	34 interacting genes: APH1B APOL3 AQP6 AVPR2 BEST1 BNIP3 CERS4 CLDN5 ERGIC3 FAM210B GPR152 GPR37L1 GPRC5D MTIF3 PGRMC2 RNF170 SLC10A1 SLC10A6 SLC16A13 SLC19A3 SLC2A13 SLC34A2 SLC35H1 SLC7A8 SPCS1 TLCD4 TMEM14B TMEM167B TMEM205 TMEM41A TMPPE TMX2 TRHR UNC93A
Entrez ID		10568	100533181
HPRD ID		07251
Ensembl ID		ENSG00000157765	ENSG00000255245
Uniprot IDs		O95436	A0A087WZ82 A0A0A6YYL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Membrane Response To Zinc Ion Endoplasmic Reticulum Membrane Regulation Of Cardiac Muscle Cell Contraction Circadian Sleep/wake Cycle, Sleep Regulation Of ATP-dependent Activity Phospholamban Complex Sarcoplasmic Reticulum Membrane Regulation Of Calcium Ion Import Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle CMP-N-acetylneuraminate Transmembrane Transporter Activity CMP-N-acetylneuraminate Transmembrane Transport 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity Regulation Of The Force Of Heart Contraction By Cardiac Conduction Calcium Ion-transporting ATPase Complex Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction	Membrane Transmembrane Transport Bile Acid:sodium Symporter Activity Symporter Activity Organic Anion Transport Renal Water Transport Carboxylic Acid Transport Organic Acid Transport Protein Binding Organic Hydroxy Compound Transport Endoplasmic Reticulum G Protein-coupled Receptor Activity Bile Acid And Bile Salt Transport
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