CXCL13 and CCL4L1

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CXCL13	CCL4L1
Description		C-X-C motif chemokine ligand 13	C-C motif chemokine ligand 4 like 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Chemokine Activity Heparin Binding Fibroblast Growth Factor Binding CXCR5 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding CXCR Chemokine Receptor Binding Receptor Ligand Activity CXCR3 Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Germinal Center Formation Lymphocyte Chemotaxis Across High Endothelial Venule Chronic Inflammatory Response Regulation Of Humoral Immune Response Chemotaxis Defense Response Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Killing Of Cells Of Another Organism Regulation Of Rap Protein Signal Transduction Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin B Cell Chemotaxis Endothelial Cell Chemotaxis To Fibroblast Growth Factor Defense Response To Bacterium Regulation Of Angiogenesis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor	Chemotaxis Inflammatory Response Immune Response Positive Regulation Of Cell Migration Eosinophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling G alpha (i) signalling events
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143) Diffusing capacity of carbon monoxide ( 30694715) Rheumatoid arthritis ( 32723749) Tonsillectomy ( 27182965 28928442) Waist circumference adjusted for body mass index ( 28552196)	Body mass index ( 26426971) Macrophage inflammatory protein 1b levels ( 27989323)
Interacting Genes		11 interacting genes: ACKR4 CCL19 CCL21 CCL28 CCL4L1 CCR10 CXCR3 CXCR5 EEF1G FGF2 PF4V1	3 interacting genes: CCL2 CXCL13 PF4V1
Entrez ID		10563	388372
HPRD ID		05513	16689
Ensembl ID		ENSG00000156234
Uniprot IDs		O43927 Q53X90	P13236 Q8NHW4
PDB IDs		5CBA 5CBE 6VGJ 7JNY	1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?		Chemotaxis Locomotion Cell Chemotaxis Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Cell Migration Cell Motility Leukocyte Migration Chemokine Activity Granulocyte Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Cytokine-mediated Signaling Pathway Cytokine Activity Granulocyte Migration Immune Response Chemokine Binding Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine Receptor Binding Antimicrobial Humoral Response Immune System Process G Protein-coupled Receptor Signaling Pathway Eosinophil Chemotaxis Eosinophil Migration Humoral Immune Response Chemokine Receptor Activity Inflammatory Response CCR7 Chemokine Receptor Binding CCR Chemokine Receptor Binding Regulation Of Sequestering Of Calcium Ion Regulation Of Dendritic Cell Dendrite Assembly Positive Regulation Of Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling Calcium-mediated Signaling Positive Regulation Of Phospholipase C/protein Kinase C Signal Transduction Cell Surface Receptor Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Regulation Of Chemotaxis Signal Transduction Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Regulation Of Leukocyte Migration C-X-C Chemokine Receptor Activity Establishment Of T Cell Polarity Negative Regulation Of Cellular Extravasation Regulation Of Cell Migration Negative Regulation Of Dendritic Cell Apoptotic Process Regulation Of Cell Motility	Chemokine Activity Granulocyte Chemotaxis Granulocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Leukocyte Chemotaxis Antimicrobial Humoral Response Cellular Response To Lipopolysaccharide CXCR Chemokine Receptor Binding Cell Chemotaxis Cellular Response To Molecule Of Bacterial Origin Cytokine Activity Leukocyte Migration Humoral Immune Response Response To Lipopolysaccharide Regulation Of Lymphocyte Chemotaxis Response To Molecule Of Bacterial Origin Chemotaxis Locomotion Cellular Response To Lipid Negative Regulation Of Chemotaxis Neutrophil Chemotaxis Lymphocyte Migration Inflammatory Response Neutrophil Migration Regulation Of Lymphocyte Migration Chemokine-mediated Signaling Pathway Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Response To Lipid Mononuclear Cell Migration Cellular Response To Oxygen-containing Compound Cell Migration Helper T Cell Extravasation Chemokine (C-C Motif) Ligand 2 Signaling Pathway CXCR5 Chemokine Receptor Binding Lymphocyte Chemotaxis Across High Endothelial Venule Endothelial Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Cell Motility Positive Regulation Of Leukocyte Migration Heparin Binding Response To Other Organism Immune Response Negative Regulation Of Natural Killer Cell Chemotaxis Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Response To External Biotic Stimulus
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