LRRC41 and KRTAP3-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LRRC41	KRTAP3-1
Description		leucine rich repeat containing 41	keratin associated protein 3-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Identical Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Protein Ubiquitination
Pathways		Neddylation RHOBTB3 ATPase cycle Antigen processing: Ubiquitination & Proteasome degradation	Keratinization
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		11 interacting genes: CYSRT1 ELOB ELOC FHL5 KRT31 KRT34 KRTAP3-1 KRTAP6-2 MYO9B RBPMS UBC	83 interacting genes: ADAM12 AGXT ANAPC11 BMP7 CDKN1A CELA2B CERK CFP CIMIP1 CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SAXO4 SLC5A5 SMARCC1 SPAG8 SPMIP9 TEKT3 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446
Entrez ID		10489	83896
HPRD ID		10102	13937
Ensembl ID		ENSG00000132128	ENSG00000212901
Uniprot IDs		Q15345	Q9BYR8
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Target-directed MiRNA Degradation Elongin Complex Keratin Filament Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Negative Regulation Of MiRNA-mediated Gene Silencing MiRNA Catabolic Process Cul5-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Epidermis Development MiRNA Metabolic Process Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Structural Molecule Activity Transcription Initiation At RNA Polymerase II Promoter Transcription Corepressor Binding Structural Constituent Of Skin Epidermis ARF Protein Signal Transduction Cytosol Intermediate Filament Organization DNA-templated Transcription Initiation Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process VCB Complex Ubiquitin Ligase Complex MRNA CDS Binding Roundabout Signaling Pathway Post-transcriptional Gene Silencing Roundabout Binding Lamellipodium Morphogenesis Protein Ubiquitination Postsynaptic Actin Cytoskeleton RNA Catabolic Process Pre-mRNA Intronic Binding Protein Modification By Small Protein Conjugation	Intermediate Filament Protein Binding Keratinization Keratin Filament Epidermis Development Axonemal A Tubule Inner Sheath Tissue Development Ventral Spinal Cord Interneuron Differentiation Heart Trabecula Morphogenesis Cellular Response To Cell-matrix Adhesion
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