CDX2 and ACAT2

Number of citations of the paper that reports this interaction (PMID 12518221)
1

Data Source:
HPRD (in vivo)

		CDX2	ACAT2
Gene Name		caudal type homeobox 2	acetyl-CoA acetyltransferase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Nuclear Chromosome Nucleoplasm Transcriptional Repressor Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity	Acetyl-CoA C-acetyltransferase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Blood Vessel Development Trophectodermal Cell Differentiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Endosome To Lysosome Transport Organ Morphogenesis Anterior/posterior Pattern Specification Somatic Stem Cell Maintenance Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Labyrinthine Layer Development	Lipid Metabolic Process
Pathways		Peptide hormone metabolism Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Incretin synthesis, secretion, and inactivation
Drugs			S-Hydroxycysteine Coenzyme A
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACAT2 CDK2 CREBBP EP300 GSK3B HNF1A MAPK1 MAPK14 PAX6 SMARCA4 SMARCB1 SMARCD1 UBB	4 interactors: CDX2 CSNK2A1 LNX1 TERF1
Entrez ID		1045	39
HPRD ID		02622	00006
Ensembl ID			ENSG00000120437
Uniprot IDs		Q99626	B7Z233 Q9BWD1
PDB IDs			1WL4 1WL5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Cellular Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Positive Regulation By Host Of Viral Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Chromatin Organization Cellular Response To Heat Nucleosome Disassembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Developmental Process Cellular Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Organ Morphogenesis Response To Heat Chromosome Organization Transcription, DNA-templated Regulation Of Wnt Signaling Pathway Cell Cycle Process RNA Biosynthetic Process Anatomical Structure Morphogenesis Interaction With Symbiont Nucleobase-containing Compound Metabolic Process N-terminal Peptidyl-lysine Acetylation Embryo Development Response To Stress Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Anatomical Structure Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Viral Transcription Cellular Nitrogen Compound Metabolic Process Innate Immune Response	Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Telomere Maintenance Via Telomere Shortening Regulation Of Cell Division Protein Homooligomerization Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Replicative Cell Aging Regulation Of Protein Catabolic Process Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Protein Processing Regulation Of Mitotic Cell Cycle Regulation Of Telomere Maintenance Via Telomerase Protein Oligomerization Negative Regulation Of Cell Cycle Positive Regulation Of Microtubule Polymerization Regulation Of Cell Cycle Process Regulation Of Telomerase Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Telomere Maintenance Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity RNA-dependent DNA Replication
Tagcloud ?		blastocyst blastocysts buffalo caspase3 caspase6 caspase7 cleave cleaving cloning competence developmental dnmt1 dnmt3a ec embryos epigenetics h3k27me3 h3k9ac handmade hdac1 hmc ivf lc nanog oct4 pluripotency produced sox2 trophectoderm	acyl acyltransferase c1 ce cholesterol cholesteryl coa cs differently elevating esterase fecal governed hamsters linoleate microsomal mtp niemann npc1l1 oleate palmitate pick raised raising regulations stearate tc triacylglycerol triacylglycerols
Tagcloud (Difference) ?		blastocyst blastocysts buffalo caspase3 caspase6 caspase7 cleave cleaving cloning competence developmental dnmt1 dnmt3a ec embryos epigenetics h3k27me3 h3k9ac handmade hdac1 hmc ivf lc nanog oct4 pluripotency produced sox2 trophectoderm	acyl acyltransferase c1 ce cholesterol cholesteryl coa cs differently elevating esterase fecal governed hamsters linoleate microsomal mtp niemann npc1l1 oleate palmitate pick raised raising regulations stearate tc triacylglycerol triacylglycerols
Tagcloud (Intersection) ?