CDX1 and CEBPA

Number of citations of the paper that reports this interaction (PMID 19059241)
1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		CDX1	CEBPA
Gene Name		caudal type homeobox 1	CCAAT/enhancer binding protein (C/EBP), alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nuclear Matrix Rb-E2F Complex
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Complex Binding Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity HMG Box Domain Binding
	Biological Process	Organ Morphogenesis Anterior/posterior Pattern Specification Positive Regulation Of Transcription From RNA Polymerase II Promoter Bone Morphogenesis	Urea Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Liver Development Embryonic Placenta Development Generation Of Precursor Metabolites And Energy Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Acute-phase Response Mitochondrion Organization Cholesterol Metabolic Process Negative Regulation Of Cell Proliferation Viral Process Cytokine-mediated Signaling Pathway Myeloid Cell Differentiation Macrophage Differentiation Lung Development Organ Regeneration Response To Vitamin B2 Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase III Promoter Cell Maturation Inner Ear Development White Fat Cell Differentiation Brown Fat Cell Differentiation Response To Glucocorticoid Cellular Response To Lithium Ion Cellular Response To Organic Cyclic Compound
Pathways			Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CEBPA LEF1 SOX2	56 interactors: AR ATF2 ATF3 ATF4 ATF5 BATF BATF2 BATF3 C1QBP CDK2 CDK4 CDKN1A CDKN3 CDX1 CEBPB CEBPD CEBPE CEBPG CREBBP CTNNB1 DBP EDF1 EP300 ESR1 FOS FOSL1 GATA2 GSK3B HNF1A MAPK8 MSX2 MYC NCOA6 NFYA NR3C1 PIAS1 RARA RARB RASGRF1 RB1 RBL1 RFC1 RUNX1 SKP2 SMAD3 SMAD4 SMARCA2 SMARCA4 SOX10 SOX8 SPI1 SRA1 SUMO3 XRCC5 XRCC6 ZBTB16
Entrez ID		1044	1050
HPRD ID		02849	00296
Ensembl ID		ENSG00000113722	ENSG00000245848
Uniprot IDs		P47902	P49715
PDB IDs
Enriched GO Terms of Interacting Partners?		Respiratory System Development Tongue Development Embryonic Organ Development Gland Development Reproductive Structure Development Reproductive System Development Sensory Organ Development Forebrain Neuron Differentiation Tube Development Developmental Process Involved In Reproduction Forebrain Generation Of Neurons Negative Regulation Of Transcription From RNA Polymerase II Promoter Diencephalon Development Response To Lipid Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Myeloid Leukocyte Differentiation Embryonic Placenta Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Osteoblast Differentiation Formation Of Primary Germ Layer Negative Regulation Of Transcription, DNA-templated Osteoblast Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Canonical Wnt Signaling Pathway Embryo Development Detection Of Mechanical Stimulus Involved In Equilibrioception Single Organism Reproductive Process Reproductive Process Glial Cell Differentiation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Inner Ear Development Negative Regulation Of Biosynthetic Process Gastrulation Placenta Development Negative Regulation Of Wnt Signaling Pathway Regulation Of Ossification Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Branching Morphogenesis Of An Epithelial Tube Pallium Development Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Apoptotic Process In Bone Marrow Regulation Of Cell Proliferation Central Nervous System Neuron Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Ear Development	Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Organ Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated System Development Multicellular Organismal Development Cellular Metabolic Process Anatomical Structure Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Cell Differentiation Regulation Of Cell Proliferation Regulation Of Cell Differentiation Tissue Development Myeloid Cell Differentiation Positive Regulation Of Cell Differentiation Regulation Of Cell Death Transcription Initiation From RNA Polymerase II Promoter
Tagcloud ?		aberrent differentiation discussed disruption embryonal f9 gamma gap43 idea impaired null overexpressing poorly ra rar rars redundancy reexpressing reexpression replace rescue responsive restored retinoic stra4 stra6 subsets supporting trans	acting additive c38 c40 caat cebpb collectively commitment composed concert elusive embryonic enhancer epidermis evolutionary fate keratinocyte keratinocytes layer modules p63 p63lre partly pluripotent pou pou3f1 redundant repress robust
Tagcloud (Difference) ?		aberrent differentiation discussed disruption embryonal f9 gamma gap43 idea impaired null overexpressing poorly ra rar rars redundancy reexpressing reexpression replace rescue responsive restored retinoic stra4 stra6 subsets supporting trans	acting additive c38 c40 caat cebpb collectively commitment composed concert elusive embryonic enhancer epidermis evolutionary fate keratinocyte keratinocytes layer modules p63 p63lre partly pluripotent pou pou3f1 redundant repress robust
Tagcloud (Intersection) ?