KLF2 and GATA5

Number of citations of the paper that reports this interaction (PMID 11375995)
17

Data Source:
BioGRID (two hybrid)

		KLF2	GATA5
Gene Name		Kruppel-like factor 2	GATA binding protein 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding Transcription Regulatory Region DNA Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Transcription, DNA-templated Negative Regulation Of Interleukin-6 Production Multicellular Organism Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Gene Expression, Epigenetic Erythrocyte Maturation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Type I Pneumocyte Differentiation Cellular Response To Hydrogen Peroxide Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Cycloheximide Cellular Response To Laminar Fluid Shear Stress Cellular Response To Peptide	Transcription From RNA Polymerase II Promoter Blood Coagulation Positive Regulation Of Transcription From RNA Polymerase II Promoter Intestinal Epithelial Cell Differentiation Cellular Response To BMP Stimulus
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		6 interactors: EP300 GATA5 GATA6 GSK3B KAT2B WWP1	3 interactors: EP300 HNF1A KLF2
Entrez ID		10365	140628
HPRD ID		03602	17029
Ensembl ID		ENSG00000127528	ENSG00000130700
Uniprot IDs		Q8IUN4 Q9Y5W3	D9ZGF7 Q9BWX5
PDB IDs
Enriched GO Terms of Interacting Partners?		N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Protein Amino Acid Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Intestinal Epithelial Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To BMP Stimulus Cellular Response To Organic Substance N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of RNA Metabolic Process Positive Regulation Of Stem Cell Differentiation Response To Organic Substance Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Heat Positive Regulation Of Protein Binding Negative Regulation Of Biosynthetic Process Muscle Structure Development Viral Process Histone H2B Acetylation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Growth Factor Stimulus Regulation Of Glucose Metabolic Process ER-nucleus Signaling Pathway Response To Growth Factor Cellular Response To Oxygen Levels Response To Heat Positive Regulation Of Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Tissue Development Positive Regulation Of Binding Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Cellular Response To Stimulus Negative Regulation Of Protein Serine/threonine Kinase Activity Histone H3-K9 Acetylation Negative Regulation Of Type B Pancreatic Cell Development	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryo Development Histone H2B Acetylation Renal Glucose Absorption Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Lung Development Respiratory Tube Development N-terminal Peptidyl-lysine Acetylation Tissue Development Respiratory System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Tubulin Deacetylation Cellular Response To Cycloheximide Paraxial Mesoderm Formation Cellular Response To Laminar Fluid Shear Stress Glucose Import Response To Oxidative Stress Transcription, DNA-templated RNA Biosynthetic Process Anatomical Structure Morphogenesis Positive Regulation By Host Of Viral Transcription Response To Cycloheximide Response To Organic Substance Positive Regulation Of Cellular Metabolic Process In Utero Embryonic Development N-terminal Protein Amino Acid Acetylation Renal Absorption Regulation Of Cytokine Production Erythrocyte Maturation Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Chromatin Modification Cellular Response To Fluid Shear Stress Response To Laminar Fluid Shear Stress Paraxial Mesoderm Morphogenesis Organ Development Positive Regulation Of DNA-templated Transcription, Initiation Reverse Cholesterol Transport Type I Pneumocyte Differentiation RNA Metabolic Process Regulation Of Androgen Receptor Signaling Pathway Tube Development
Tagcloud ?		92a ameliorates atherogenesis attenuates bioavailability challenged disrupts dysfunctional ecs enos exacerbates hypercholesterolemic inflammasome infused innate klf4 kruppel lna locked microrna nlrp3 nucleic postulated pyrin sirtuin srebp2 sterol stresses vasodilation	aberrant alternative arrdc3 carcinomas cpg detect ductal elp3 explore follows frequency grades hypermethylation idcs inactivate inactivation islands lower lymph matched methylated methylation mnts node pax6 promoter represents suppressor unmethylated
Tagcloud (Difference) ?		92a ameliorates atherogenesis attenuates bioavailability challenged disrupts dysfunctional ecs enos exacerbates hypercholesterolemic inflammasome infused innate klf4 kruppel lna locked microrna nlrp3 nucleic postulated pyrin sirtuin srebp2 sterol stresses vasodilation	aberrant alternative arrdc3 carcinomas cpg detect ductal elp3 explore follows frequency grades hypermethylation idcs inactivate inactivation islands lower lymph matched methylated methylation mnts node pax6 promoter represents suppressor unmethylated
Tagcloud (Intersection) ?